Clocapramine has been implicated in at least one fatality, a suicide in which there were two self-inflicted stab wounds and an
overdose of clocapramine as well as three other antipsychotics was taken.[15] The stab wounds could not explain the death, and thus, it was attributed to multiple drug toxicity instead.[15]
^
abcSumiyoshi T, Suzuki K, Sakamoto H, et al. (February 1995). "Atypicality of several antipsychotics on the basis of in vivo dopamine-D2 and serotonin-5HT2 receptor occupancy". Neuropsychopharmacology. 12 (1): 57–64.
doi:
10.1016/0893-133X(94)00064-7.
PMID7766287.
^Kurihara M, Tsumagari T, Setoguchi M, Fukuda T (1982). "A study on the pharmacological and biochemical profile of clocapramine". International Pharmacopsychiatry. 17 (2): 73–90.
doi:
10.1159/000468561.
PMID6125486.
^Tsukamoto T, Asakura M, Hirata N, Imafuku J, Matsui H, Hasegawa K (September 1984). "Interaction of neuroleptics and antidepressants with rat brain alpha 2-receptors: a possible relationship between alpha 2-receptor antagonism and antidepressant action". Biological Psychiatry. 19 (9): 1283–91.
PMID6149771.
^Setoguchi M, Sakamori M, Takehara S, Fukuda T (June 1985). "Effects of iminodibenzyl antipsychotic drugs on cerebral dopamine and alpha-adrenergic receptors". European Journal of Pharmacology. 112 (3): 313–22.
doi:
10.1016/0014-2999(85)90776-9.
PMID2862053.
^Morio Y, Tanimoto H, Yakushiji T, Morimoto Y (February 1994). "Characterization of the currents induced by sigma ligands in NCB20 neuroblastoma cells". Brain Research. 637 (1–2): 190–6.
doi:
10.1016/0006-8993(94)91232-7.
PMID7910100.
S2CID19250949.
^Yamagami S (1985). "A crossover study of clocapramine and haloperidol in chronic schizophrenia". The Journal of International Medical Research. 13 (6): 301–10.
doi:
10.1177/030006058501300601.
PMID4076529.
S2CID16157745.
^Yamagami S, Kiriike N, Kawaguchi K (1988). "A single-blind study of clocapramine and sulpiride in hospitalized chronic schizophrenic patients". Drugs Under Experimental and Clinical Research. 14 (11): 707–13.
PMID3246215.
^Nakazawa T, Ohara K, Sawa Y, et al. (1983). "Comparison of efficacy of timiperone, a new butyrophenone derivative, and clocapramine in schizophrenia: a multiclinic double-blind study". The Journal of International Medical Research. 11 (5): 247–58.
doi:
10.1177/030006058301100501.
PMID6139317.
S2CID25624985.
^
abKoreeda A, Yonemitsu K, Ng'walali PM, Muraoka N, Tsunenari S (October 2001). "Clocapramine-related fatality. Postmortem drug levels in multiple psychoactive drug poisoning". Forensic Science International. 122 (1): 48–51.
doi:
10.1016/S0379-0738(01)00442-X.
PMID11587865.
Clocapramine has been implicated in at least one fatality, a suicide in which there were two self-inflicted stab wounds and an
overdose of clocapramine as well as three other antipsychotics was taken.[15] The stab wounds could not explain the death, and thus, it was attributed to multiple drug toxicity instead.[15]
^
abcSumiyoshi T, Suzuki K, Sakamoto H, et al. (February 1995). "Atypicality of several antipsychotics on the basis of in vivo dopamine-D2 and serotonin-5HT2 receptor occupancy". Neuropsychopharmacology. 12 (1): 57–64.
doi:
10.1016/0893-133X(94)00064-7.
PMID7766287.
^Kurihara M, Tsumagari T, Setoguchi M, Fukuda T (1982). "A study on the pharmacological and biochemical profile of clocapramine". International Pharmacopsychiatry. 17 (2): 73–90.
doi:
10.1159/000468561.
PMID6125486.
^Tsukamoto T, Asakura M, Hirata N, Imafuku J, Matsui H, Hasegawa K (September 1984). "Interaction of neuroleptics and antidepressants with rat brain alpha 2-receptors: a possible relationship between alpha 2-receptor antagonism and antidepressant action". Biological Psychiatry. 19 (9): 1283–91.
PMID6149771.
^Setoguchi M, Sakamori M, Takehara S, Fukuda T (June 1985). "Effects of iminodibenzyl antipsychotic drugs on cerebral dopamine and alpha-adrenergic receptors". European Journal of Pharmacology. 112 (3): 313–22.
doi:
10.1016/0014-2999(85)90776-9.
PMID2862053.
^Morio Y, Tanimoto H, Yakushiji T, Morimoto Y (February 1994). "Characterization of the currents induced by sigma ligands in NCB20 neuroblastoma cells". Brain Research. 637 (1–2): 190–6.
doi:
10.1016/0006-8993(94)91232-7.
PMID7910100.
S2CID19250949.
^Yamagami S (1985). "A crossover study of clocapramine and haloperidol in chronic schizophrenia". The Journal of International Medical Research. 13 (6): 301–10.
doi:
10.1177/030006058501300601.
PMID4076529.
S2CID16157745.
^Yamagami S, Kiriike N, Kawaguchi K (1988). "A single-blind study of clocapramine and sulpiride in hospitalized chronic schizophrenic patients". Drugs Under Experimental and Clinical Research. 14 (11): 707–13.
PMID3246215.
^Nakazawa T, Ohara K, Sawa Y, et al. (1983). "Comparison of efficacy of timiperone, a new butyrophenone derivative, and clocapramine in schizophrenia: a multiclinic double-blind study". The Journal of International Medical Research. 11 (5): 247–58.
doi:
10.1177/030006058301100501.
PMID6139317.
S2CID25624985.
^
abKoreeda A, Yonemitsu K, Ng'walali PM, Muraoka N, Tsunenari S (October 2001). "Clocapramine-related fatality. Postmortem drug levels in multiple psychoactive drug poisoning". Forensic Science International. 122 (1): 48–51.
doi:
10.1016/S0379-0738(01)00442-X.
PMID11587865.