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CAS Number | |
PubChem CID | |
ChemSpider | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C19H20BrNO2 |
Molar mass | 374.278 g·mol−1 |
3D model ( JSmol) | |
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(what is this?) (verify) |
6-Br-APB is a synthetic compound that acts as a selective D1 agonist, [1] with the (R)- enantiomer being a potent full agonist, while the (S) enantiomer retains its D1 selectivity but is a weak partial agonist. [2] (R)-6-Br-APB and similar D1-selective full agonists like SKF-81,297 and SKF-82,958 produce characteristic anorectic effects, stereotyped behaviour and self-administration in animals, with a similar but not identical profile to that of dopaminergic stimulants such as amphetamine. [3] [4] [5]
Identifiers | |
---|---|
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C19H20BrNO2 |
Molar mass | 374.278 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(what is this?) (verify) |
6-Br-APB is a synthetic compound that acts as a selective D1 agonist, [1] with the (R)- enantiomer being a potent full agonist, while the (S) enantiomer retains its D1 selectivity but is a weak partial agonist. [2] (R)-6-Br-APB and similar D1-selective full agonists like SKF-81,297 and SKF-82,958 produce characteristic anorectic effects, stereotyped behaviour and self-administration in animals, with a similar but not identical profile to that of dopaminergic stimulants such as amphetamine. [3] [4] [5]