Clinical data | |
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Trade names | Barnetil, Barnotil, Topral |
AHFS/ Drugs.com | International Drug Names |
Routes of administration | Oral, IM |
ATC code | |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Elimination half-life | 3–5 hours |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.053.293 |
Chemical and physical data | |
Formula | C17H26N2O4S |
Molar mass | 354.47 g·mol−1 |
3D model ( JSmol) | |
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(what is this?) (verify) |
Sultopride (trade names Barnetil, Barnotil, Topral) is an atypical antipsychotic of the benzamide chemical class used in Europe, Japan, and Hong Kong for the treatment of schizophrenia. [2] [3] [4] It was launched by Sanofi-Aventis in 1976. [2] Sultopride acts as a selective D2 and D3 receptor antagonist. [5] It has also been shown to have clinically relevant affinity for the GHB receptor as well, a property it shares in common with amisulpride and sulpiride. [6]
Site | Ki | Species | Ref |
---|---|---|---|
D2 | 1.6 | Human | [7] |
D3 | 3.8 | Human | [7] |
Clinical data | |
---|---|
Trade names | Barnetil, Barnotil, Topral |
AHFS/ Drugs.com | International Drug Names |
Routes of administration | Oral, IM |
ATC code | |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Elimination half-life | 3–5 hours |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.053.293 |
Chemical and physical data | |
Formula | C17H26N2O4S |
Molar mass | 354.47 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(what is this?) (verify) |
Sultopride (trade names Barnetil, Barnotil, Topral) is an atypical antipsychotic of the benzamide chemical class used in Europe, Japan, and Hong Kong for the treatment of schizophrenia. [2] [3] [4] It was launched by Sanofi-Aventis in 1976. [2] Sultopride acts as a selective D2 and D3 receptor antagonist. [5] It has also been shown to have clinically relevant affinity for the GHB receptor as well, a property it shares in common with amisulpride and sulpiride. [6]
Site | Ki | Species | Ref |
---|---|---|---|
D2 | 1.6 | Human | [7] |
D3 | 3.8 | Human | [7] |