Names | |
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IUPAC name
1-{2-[Bis(4-fluorophenyl)methoxy]ethyl}-4-[3-(4-fluorophenyl)propyl]piperazine;methanesulfonic acid
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Identifiers | |
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3D model (
JSmol)
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ChEMBL |
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ChemSpider | |
PubChem
CID
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Properties | |
C30H39F3N2O7S2 | |
Molar mass | 660.76 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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GBR-13098 is a psychostimulant and selective dopamine uptake inhibitor. [1]
Blocking the endogenous striatal dopamine (DA) transporter with GBR-13098 in mice has been shown to prevent damage to the DA nerve terminals caused by malonate. It was suggested that DA transporter inhibitors like GBR-13098 could be used to prevent or treat neurodegenerative disorders caused by the effect of mitochondrial dysfunction on DA homeostasis. [2]
Simple piperazines (no additional rings) | |
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Phenylpiperazines |
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Benzylpiperazines | |
Diphenylalkylpiperazines (benzhydrylalkylpiperazines) |
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Pyrimidinylpiperazines | |
Pyridinylpiperazines | |
Benzo(iso)thiazolyl piperazines | |
Tricyclics (piperazine attached via side chain) |
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Others/Uncategorized |
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |
Names | |
---|---|
IUPAC name
1-{2-[Bis(4-fluorophenyl)methoxy]ethyl}-4-[3-(4-fluorophenyl)propyl]piperazine;methanesulfonic acid
| |
Identifiers | |
| |
3D model (
JSmol)
|
|
ChEMBL |
|
ChemSpider | |
PubChem
CID
|
|
| |
| |
Properties | |
C30H39F3N2O7S2 | |
Molar mass | 660.76 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
GBR-13098 is a psychostimulant and selective dopamine uptake inhibitor. [1]
Blocking the endogenous striatal dopamine (DA) transporter with GBR-13098 in mice has been shown to prevent damage to the DA nerve terminals caused by malonate. It was suggested that DA transporter inhibitors like GBR-13098 could be used to prevent or treat neurodegenerative disorders caused by the effect of mitochondrial dysfunction on DA homeostasis. [2]
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Adenosine antagonists | |
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Ampakines | |
Arylcyclohexylamines | |
Benzazepines | |
Cathinones |
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Cholinergics |
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Convulsants | |
Eugeroics | |
Oxazolines | |
Phenethylamines |
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Phenylmorpholines | |
Piperazines | |
Piperidines |
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Pyrrolidines | |
Racetams | |
Tropanes |
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Tryptamines | |
Others |
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DATTooltip Dopamine transporter ( DRIsTooltip Dopamine reuptake inhibitors) |
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NETTooltip Norepinephrine transporter ( NRIsTooltip Norepinephrine reuptake inhibitors) |
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SERTTooltip Serotonin transporter ( SRIsTooltip Serotonin reuptake inhibitors) |
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VMATsTooltip Vesicular monoamine transporters | |||||||||||||||
Others |
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Simple piperazines (no additional rings) | |
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Phenylpiperazines |
|
Benzylpiperazines | |
Diphenylalkylpiperazines (benzhydrylalkylpiperazines) |
|
Pyrimidinylpiperazines | |
Pyridinylpiperazines | |
Benzo(iso)thiazolyl piperazines | |
Tricyclics (piperazine attached via side chain) |
|
Others/Uncategorized |
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |