From Wikipedia, the free encyclopedia
Levodropropizine
Clinical data
AHFS/ Drugs.com International Drug Names
ATC code
Pharmacokinetic data
Protein binding11-14%
Excretion83% via urine within 96 h
Identifiers
  • (2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard ( EPA)
ECHA InfoCard 100.167.719 Edit this at Wikidata
Chemical and physical data
FormulaC13H20N2O2
Molar mass236.315 g·mol−1
3D model ( JSmol)
  • O[C@@H](CN2CCN(c1ccccc1)CC2)CO
  • InChI=1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2/t13-/m0/s1 checkY
  • Key:PTVWPYVOOKLBCG-ZDUSSCGKSA-N checkY
 ☒NcheckY  (what is this?)   (verify)

Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system. [1] It does not cause side effects such as constipation or respiratory depression which can be produced by opioid antitussives such as codeine and its derivatives.

References

  1. ^ De Blasio F, Dicpinigaitis PV, Rubin BK, De Danieli G, Lanata L, Zanasi A (January 2012). "An observational study on cough in children: epidemiology, impact on quality of sleep and treatment outcome". Cough. 8 (1): 1. doi: 10.1186/1745-9974-8-1. PMC  3274450. PMID  22269875.


From Wikipedia, the free encyclopedia
Levodropropizine
Clinical data
AHFS/ Drugs.com International Drug Names
ATC code
Pharmacokinetic data
Protein binding11-14%
Excretion83% via urine within 96 h
Identifiers
  • (2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
CompTox Dashboard ( EPA)
ECHA InfoCard 100.167.719 Edit this at Wikidata
Chemical and physical data
FormulaC13H20N2O2
Molar mass236.315 g·mol−1
3D model ( JSmol)
  • O[C@@H](CN2CCN(c1ccccc1)CC2)CO
  • InChI=1S/C13H20N2O2/c16-11-13(17)10-14-6-8-15(9-7-14)12-4-2-1-3-5-12/h1-5,13,16-17H,6-11H2/t13-/m0/s1 checkY
  • Key:PTVWPYVOOKLBCG-ZDUSSCGKSA-N checkY
 ☒NcheckY  (what is this?)   (verify)

Levodropropizine is a cough suppressant. It is the levo isomer of dropropizine. It acts as a peripheral antitussive, with no action in the central nervous system. [1] It does not cause side effects such as constipation or respiratory depression which can be produced by opioid antitussives such as codeine and its derivatives.

References

  1. ^ De Blasio F, Dicpinigaitis PV, Rubin BK, De Danieli G, Lanata L, Zanasi A (January 2012). "An observational study on cough in children: epidemiology, impact on quality of sleep and treatment outcome". Cough. 8 (1): 1. doi: 10.1186/1745-9974-8-1. PMC  3274450. PMID  22269875.



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