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Routes of administration | Oral |
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Formula | C20H25NO |
Molar mass | 295.426 g·mol−1 |
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Difemetorex ( INN; sold as Cleofil; also known as diphemethoxidine) is a stimulant drug of the piperidine class which was used as an appetite suppressant, but produced intolerable side effects such as insomnia which limited its clinical use. [1] [2] [3] [4] [5] It was introduced in France by Ciba-Geigy in 1966 but is now no longer marketed. [6]
Alkylation of desoxypipradrol with ethylene oxide gives difemetorex. [7]
DATTooltip Dopamine transporter ( DRIsTooltip Dopamine reuptake inhibitors) |
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NETTooltip Norepinephrine transporter ( NRIsTooltip Norepinephrine reuptake inhibitors) |
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SERTTooltip Serotonin transporter ( SRIsTooltip Serotonin reuptake inhibitors) |
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VMATsTooltip Vesicular monoamine transporters | |||||||||||||||
Others |
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Clinical data | |
---|---|
Routes of administration | Oral |
ATC code |
|
Legal status | |
Legal status |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
ChEMBL | |
Chemical and physical data | |
Formula | C20H25NO |
Molar mass | 295.426 g·mol−1 |
3D model ( JSmol) | |
|
Difemetorex ( INN; sold as Cleofil; also known as diphemethoxidine) is a stimulant drug of the piperidine class which was used as an appetite suppressant, but produced intolerable side effects such as insomnia which limited its clinical use. [1] [2] [3] [4] [5] It was introduced in France by Ciba-Geigy in 1966 but is now no longer marketed. [6]
Alkylation of desoxypipradrol with ethylene oxide gives difemetorex. [7]
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DATTooltip Dopamine transporter ( DRIsTooltip Dopamine reuptake inhibitors) |
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SERTTooltip Serotonin transporter ( SRIsTooltip Serotonin reuptake inhibitors) |
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VMATsTooltip Vesicular monoamine transporters | |||||||||||||||
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