From Wikipedia, the free encyclopedia
Mebhydrolin
Clinical data
Other names9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, Diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate [1]
AHFS/ Drugs.com International Drug Names
Pregnancy
category
  • Not established [2]
Routes of
administration
Oral [2]
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
CAS Number
  • 524-81-2 checkY
    6153-33-9 (1,5-naphthalenedisulfonate salt) [3]
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard ( EPA)
ECHA InfoCard 100.007.606 Edit this at Wikidata
Chemical and physical data
FormulaC19H20N2 [4]
Molar mass276.383 g·mol−1
3D model ( JSmol)
  • CN3Cc4c1ccccc1n(Cc2ccccc2)c4CC3
  • InChI=1S/C19H20N2/c1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3 checkY
  • Key:FQQIIPAOSKSOJM-UHFFFAOYSA-N checkY
 ☒NcheckY  (what is this?)   (verify)

Mebhydrolin ( INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal ( BD) and Diazolin ( RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to magnify the performance-deficit effects of alcohol. [5]

References

  1. ^ "Mebhydroline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
  2. ^ a b "FABAHISTIN 50 mg (Tablets)". South African Electronic Package Inserts. September 1970. Archived from the original on October 17, 2006. Retrieved 2007-03-02.
  3. ^ "Diazoline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
  4. ^ "Mebhydrolin chemical information". PubChem. Retrieved 2007-03-02.
  5. ^ Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust. 2 (9): 477–9. doi: 10.5694/j.1326-5377.1981.tb112944.x. PMID  6119605. S2CID  11034501.
From Wikipedia, the free encyclopedia
Mebhydrolin
Clinical data
Other names9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, Diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate [1]
AHFS/ Drugs.com International Drug Names
Pregnancy
category
  • Not established [2]
Routes of
administration
Oral [2]
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
CAS Number
  • 524-81-2 checkY
    6153-33-9 (1,5-naphthalenedisulfonate salt) [3]
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard ( EPA)
ECHA InfoCard 100.007.606 Edit this at Wikidata
Chemical and physical data
FormulaC19H20N2 [4]
Molar mass276.383 g·mol−1
3D model ( JSmol)
  • CN3Cc4c1ccccc1n(Cc2ccccc2)c4CC3
  • InChI=1S/C19H20N2/c1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3 checkY
  • Key:FQQIIPAOSKSOJM-UHFFFAOYSA-N checkY
 ☒NcheckY  (what is this?)   (verify)

Mebhydrolin ( INN) or mebhydroline is an antihistamine. It is not available in the United States, but it is in various other countries under the brand names Bexidal ( BD) and Diazolin ( RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to magnify the performance-deficit effects of alcohol. [5]

References

  1. ^ "Mebhydroline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
  2. ^ a b "FABAHISTIN 50 mg (Tablets)". South African Electronic Package Inserts. September 1970. Archived from the original on October 17, 2006. Retrieved 2007-03-02.
  3. ^ "Diazoline". National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved 2007-03-02.
  4. ^ "Mebhydrolin chemical information". PubChem. Retrieved 2007-03-02.
  5. ^ Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin". Med. J. Aust. 2 (9): 477–9. doi: 10.5694/j.1326-5377.1981.tb112944.x. PMID  6119605. S2CID  11034501.

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