MEDRYLAMINE

Medrylamine
Identifiers
	IUPAC name 2-[(4-methoxyphenyl)-phenylmethoxy]-N,N-dimethylethanamine;
CAS Number	524-99-2 ;
PubChem CID	10669;
ChemSpider	10219 ;
UNII	5R003655CR;
ChEBI	CHEBI:135181;
ChEMBL	ChEMBL2104714 ;
ECHA InfoCard	100.007.609
Chemical and physical data
Formula	C18H23NO2
Molar mass	285.387 g·mol−1
3D model ( JSmol)	Interactive image;
	SMILES CN(C)CCOC(c1ccccc1)c2ccc(cc2)OC;
	InChI InChI=InChI=1S/C18H23NO2/c1-19(2)13-14-21-18(15-7-5-4-6-8-15)16-9-11-17(20-3)12-10-16/h4-12,18H,13-14H2,1-3H3 ; Key:BXCMCXBSUDRYPF-UHFFFAOYSA-N ;

Medrylamine is an antihistamine related to diphenhydramine.^[1]^[2]

References

^ US 2668856, Morren H, "P-methoxy benzhydryl ethers", issued 1954, assigned to UCB SA.
^ Wolff ME (1995). Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents. Vol. 5 (5th ed.). New York: Wiley. p. 518. ISBN 978-0-471-57560-3.

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[1] US 2668856, Morren H, "P-methoxy benzhydryl ethers", issued 1954, assigned to UCB SA.

[2] Wolff ME (1995). Burger's Medicinal Chemistry and Drug Discovery, Therapeutic Agents. Vol. 5 (5th ed.). New York: Wiley. p. 518. ISBN 978-0-471-57560-3.

[1]

[2]

v t e Antihistamines ( R06)
Benzimidazoles ( *)	Astemizole Azelastine Bilastine Emedastine Mizolastine Talastine
Diarylmethanes	Diarylmethoxyalkylamines: Bromazine (bromodiphenhydramine) Carbinoxamine Chlorphenoxamine Clemastine Diphenhydramine ( +naproxen) Diphenylpyraline Doxylamine Ebastine Orphenadrine Diphenylmethanolpiperidines: Fexofenadine Terfenadine Diphenylmethylpiperazines: Buclizine Cetirizine Levocetirizine Chlorcyclizine Cinnarizine Cyclizine Etodroxizine Hydroxyzine Meclizine Oxatomide Phenylpyridinylpropanamines: Brompheniramine Chlorphenamine Dexbrompheniramine ( +pseudoephedrine) Dexchlorpheniramine ( +betamethasone) Pheniramine Others: Acrivastine Bamipine Dimetindene Phenyltoloxamine Pyrrobutamine Quifenadine Triprolidine
Ethylenediamines	Antazoline Chloropyramine Histapyrrodine Mepyramine (pyrilamine) Methapyrilene Phenbenzamine Thenalidine Tripelennamine (pyribenzamine)
Tricyclics	Dibenzocycloheptenes: Antidepressants (e.g., amitriptyline) Azatadine Cyproheptadine Deptropine Desloratadine Ketotifen Loratadine Rupatadine Phenothiazines: Alimemazine Fenethazine Hydroxyethylpromethazine Isothipendyl Mequitazine Methdilazine Oxomemazine Promethazine Others: Antidepressants (e.g., doxepin, mirtazapine, trimipramine) Epinastine Latrepirdine Mebhydrolin Olopatadine Perlapine Phenindamine Pimethixene
Others	Phenylpiperazines: Antidepressants (e.g., trazodone) Phenbenzamine
For topical use	Bamipine Chloropyramine Chlorphenoxamine Clemastine Dimetindene Diphenhydramine Doxepin Isothipendyl Mepyramine (pyrilamine) Promethazine

v t e Antihistamines ( R06)
Benzimidazoles ( *)	Astemizole Azelastine Bilastine Emedastine Mizolastine Talastine
Diarylmethanes	Diarylmethoxyalkylamines: Bromazine (bromodiphenhydramine) Carbinoxamine Chlorphenoxamine Clemastine Diphenhydramine ( +naproxen) Diphenylpyraline Doxylamine Ebastine Orphenadrine Diphenylmethanolpiperidines: Fexofenadine Terfenadine Diphenylmethylpiperazines: Buclizine Cetirizine Levocetirizine Chlorcyclizine Cinnarizine Cyclizine Etodroxizine Hydroxyzine Meclizine Oxatomide Phenylpyridinylpropanamines: Brompheniramine Chlorphenamine Dexbrompheniramine ( +pseudoephedrine) Dexchlorpheniramine ( +betamethasone) Pheniramine Others: Acrivastine Bamipine Dimetindene Phenyltoloxamine Pyrrobutamine Quifenadine Triprolidine
Ethylenediamines	Antazoline Chloropyramine Histapyrrodine Mepyramine (pyrilamine) Methapyrilene Phenbenzamine Thenalidine Tripelennamine (pyribenzamine)
Tricyclics	Dibenzocycloheptenes: Antidepressants (e.g., amitriptyline) Azatadine Cyproheptadine Deptropine Desloratadine Ketotifen Loratadine Rupatadine Phenothiazines: Alimemazine Fenethazine Hydroxyethylpromethazine Isothipendyl Mequitazine Methdilazine Oxomemazine Promethazine Others: Antidepressants (e.g., doxepin, mirtazapine, trimipramine) Epinastine Latrepirdine Mebhydrolin Olopatadine Perlapine Phenindamine Pimethixene
Others	Phenylpiperazines: Antidepressants (e.g., trazodone) Phenbenzamine
For topical use	Bamipine Chloropyramine Chlorphenoxamine Clemastine Dimetindene Diphenhydramine Doxepin Isothipendyl Mepyramine (pyrilamine) Promethazine

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Identifiers

IUPAC name 2-[(4-methoxyphenyl)-phenylmethoxy]-N,N-dimethylethanamine
CAS Number	524-99-2^Y
PubChem CID	10669
ChemSpider	10219^Y
UNII	5R003655CR
ChEBI	CHEBI:135181
ChEMBL	ChEMBL2104714^Y
ECHA InfoCard	100.007.609
Chemical and physical data
Formula	C₁₈H₂₃NO₂
Molar mass	285.387 g·mol⁻¹
3D model ( JSmol)	Interactive image
SMILES CN(C)CCOC(c1ccccc1)c2ccc(cc2)OC
InChI InChI=InChI=1S/C18H23NO2/c1-19(2)13-14-21-18(15-7-5-4-6-8-15)16-9-11-17(20-3)12-10-16/h4-12,18H,13-14H2,1-3H3^Y Key:BXCMCXBSUDRYPF-UHFFFAOYSA-N^Y