Its use for these indications was limited by
side effects such as
dry mouth and
nausea, and at high doses it can cause more severe symptoms such as
deliriant and
hallucinogenic effects.[2] "Large doses of benactyzine in normal subjects may produce a state resembling the action of
mescaline or
LSD."[3]
Brand names have included: Suavitil, Phebex, Phobex, Cedad, Cevanol, Deprol, Lucidil, Morcain, Nutinal, Parasan. While there was some tentative evidence of effectiveness when combined with
meprobamate, with the medication no longer available it is not clinically important.[4]
History
Benactyzine was brought to market in the US in 1957 by
Merck under the tradename, Suavitil.[5]
^
abShorter E (December 2002). "Looking backwards: a possible new path for drug discovery in psychopharmacology". Nature Reviews. Drug Discovery. 1 (12): 1003–1006.
doi:
10.1038/nrd964.
PMID12461521.
S2CID23439533.
^Fisher S (1959). Child Research In Psychopharmacology (1st ed.). Springfield, Illinois: Charles C Thomas Pub. p. 13.
Its use for these indications was limited by
side effects such as
dry mouth and
nausea, and at high doses it can cause more severe symptoms such as
deliriant and
hallucinogenic effects.[2] "Large doses of benactyzine in normal subjects may produce a state resembling the action of
mescaline or
LSD."[3]
Brand names have included: Suavitil, Phebex, Phobex, Cedad, Cevanol, Deprol, Lucidil, Morcain, Nutinal, Parasan. While there was some tentative evidence of effectiveness when combined with
meprobamate, with the medication no longer available it is not clinically important.[4]
History
Benactyzine was brought to market in the US in 1957 by
Merck under the tradename, Suavitil.[5]
^
abShorter E (December 2002). "Looking backwards: a possible new path for drug discovery in psychopharmacology". Nature Reviews. Drug Discovery. 1 (12): 1003–1006.
doi:
10.1038/nrd964.
PMID12461521.
S2CID23439533.
^Fisher S (1959). Child Research In Psychopharmacology (1st ed.). Springfield, Illinois: Charles C Thomas Pub. p. 13.