Clinical data | |
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AHFS/ Drugs.com | International Drug Names |
ATC code | |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.055.494 |
Chemical and physical data | |
Formula | C21H27N |
Molar mass | 293.454 g·mol−1 |
3D model ( JSmol) | |
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| |
(verify) |
Budipine (brand name Parkinsan) is an antiparkinson agent marketed for the treatment of Parkinson's disease. [2] [3] [4]
While its exact mechanism of action is not well characterized, [2] it is believed to be an NMDA receptor antagonist, [5] [6] but also promoting the synthesis of dopamine. [7]
Because it provides additional benefits relative to existing treatments, it probably does not precisely mimic the mechanism of an existing known treatment. [7] [8]
Budipine can be prepared from the 1-tert-butyl-4-piperidone [1465-76-5] directly by treatment with benzene in the presence triflic acid. [9] This method of synthesis enables a 99% yield of product.
4-Phenyl-1-t-butyl-4-piperidinol, [11] (1)
1-t-butyl-3-benzoyl-4-phenyl-4-piperidinol [81831-81-4] (3)
{{
cite book}}
: |journal=
ignored (
help)
Clinical data | |
---|---|
AHFS/ Drugs.com | International Drug Names |
ATC code | |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.055.494 |
Chemical and physical data | |
Formula | C21H27N |
Molar mass | 293.454 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(verify) |
Budipine (brand name Parkinsan) is an antiparkinson agent marketed for the treatment of Parkinson's disease. [2] [3] [4]
While its exact mechanism of action is not well characterized, [2] it is believed to be an NMDA receptor antagonist, [5] [6] but also promoting the synthesis of dopamine. [7]
Because it provides additional benefits relative to existing treatments, it probably does not precisely mimic the mechanism of an existing known treatment. [7] [8]
Budipine can be prepared from the 1-tert-butyl-4-piperidone [1465-76-5] directly by treatment with benzene in the presence triflic acid. [9] This method of synthesis enables a 99% yield of product.
4-Phenyl-1-t-butyl-4-piperidinol, [11] (1)
1-t-butyl-3-benzoyl-4-phenyl-4-piperidinol [81831-81-4] (3)
{{
cite book}}
: |journal=
ignored (
help)