ALPHA-METHYLHISTAMINE

α-Methylhistamine
Names
	IUPAC name 1-(3H-Imidazol-4-yl)propan-2-amine
	Systematic IUPAC name 1-(1H-Imidazol-4-yl)propan-2-amine
Identifiers
CAS Number	6986-90-9 ; 75614-87-8 (R) ; 75614-93-6 (S) ;
3D model ( JSmol)	Interactive image;
ChEBI	CHEBI:295965 ;
ChEMBL	ChEMBL116655 ;
ChemSpider	3489 ;
IUPHAR/BPS	1239;
MeSH	Alpha-methylhistamine
PubChem CID	3615; 156615 (R); 6603865 (S);
CompTox Dashboard ( EPA)	DTXSID80990132 ;
	InChI InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9) Key: XNQIOISZPFVUFG-UHFFFAOYSA-N ; InChI=1/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9) Key: XNQIOISZPFVUFG-UHFFFAOYAW;
	SMILES CC(N)CC1=CNC=N1;
Properties
Chemical formula	C6H11N3
Molar mass	125.175 g·mol−1
log P	-0.346
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify ( what is ?) Infobox references

α-Methylhistamine is a histamine agonist selective for the receptor subtype H₃. It causes lowering of blood pressure and a decrease of heart rate in animal models.^[2]

References

^ "Chemical Entities of Biological Interest (ChEBI)".
^ McLeod, RL; Gertner, SB; Hey, JA (1993). "Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs". Br J Pharmacol. 110 (2): 553–558. doi: 10.1111/j.1476-5381.1993.tb13846.x. PMC 2175947. PMID 7902173.

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[1] "Chemical Entities of Biological Interest (ChEBI)".

[2] McLeod, RL; Gertner, SB; Hey, JA (1993). "Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs". Br J Pharmacol. 110 (2): 553–558. doi: 10.1111/j.1476-5381.1993.tb13846.x. PMC 2175947. PMID 7902173.

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