From Wikipedia, the free encyclopedia
Arformoterol
Clinical data
Trade namesBrovana
Other namesArformoterol tartrate ( USAN US)
AHFS/ Drugs.com Monograph
MedlinePlus a602023
License data
Routes of
administration
Inhalation
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
Protein binding52–65%
Elimination half-life26 hours
Identifiers
  • N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl) propan-2-yl]amino]ethyl] phenyl]formamide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard ( EPA)
Chemical and physical data
FormulaC19H24N2O4
Molar mass344.411 g·mol−1
  • InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1 checkY
  • Key:BPZSYCZIITTYBL-YJYMSZOUSA-N checkY
 ☒NcheckY  (what is this?)   (verify)

Arformoterol, sold under the brand name Brovana among others, is a medication used for the treatment of chronic obstructive pulmonary disease (COPD). [1] [2]

It is a long-acting β2 adrenoreceptor agonist (LABA) and it is the active (R,R)-(−)- enantiomer of formoterol. [1] It was approved for medical use in the United States in October 2006. [1] It is available as a generic medication. [3]

Medical uses

Arformoterol is indicated for the maintenance treatment of bronchoconstriction in people with chronic obstructive pulmonary disease (COPD). [1]

References

  1. ^ a b c d e "Brovana- arformoterol tartrate solution". DailyMed. 13 May 2021. Retrieved 4 March 2022.
  2. ^ Loh CH, Donohue JF, Ohar JA (March 2015). "Review of drug safety and efficacy of arformoterol in chronic obstructive pulmonary disease". Expert Opinion on Drug Safety. 14 (3): 463–72. doi: 10.1517/14740338.2015.998196. PMID  25563342. S2CID  7767810.
  3. ^ "Competitive Generic Therapy Approvals". U.S. Food and Drug Administration (FDA). 29 June 2023. Archived from the original on 29 June 2023. Retrieved 29 June 2023.

External links


From Wikipedia, the free encyclopedia
Arformoterol
Clinical data
Trade namesBrovana
Other namesArformoterol tartrate ( USAN US)
AHFS/ Drugs.com Monograph
MedlinePlus a602023
License data
Routes of
administration
Inhalation
ATC code
  • None
Legal status
Legal status
Pharmacokinetic data
Protein binding52–65%
Elimination half-life26 hours
Identifiers
  • N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl) propan-2-yl]amino]ethyl] phenyl]formamide
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard ( EPA)
Chemical and physical data
FormulaC19H24N2O4
Molar mass344.411 g·mol−1
  • InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1 checkY
  • Key:BPZSYCZIITTYBL-YJYMSZOUSA-N checkY
 ☒NcheckY  (what is this?)   (verify)

Arformoterol, sold under the brand name Brovana among others, is a medication used for the treatment of chronic obstructive pulmonary disease (COPD). [1] [2]

It is a long-acting β2 adrenoreceptor agonist (LABA) and it is the active (R,R)-(−)- enantiomer of formoterol. [1] It was approved for medical use in the United States in October 2006. [1] It is available as a generic medication. [3]

Medical uses

Arformoterol is indicated for the maintenance treatment of bronchoconstriction in people with chronic obstructive pulmonary disease (COPD). [1]

References

  1. ^ a b c d e "Brovana- arformoterol tartrate solution". DailyMed. 13 May 2021. Retrieved 4 March 2022.
  2. ^ Loh CH, Donohue JF, Ohar JA (March 2015). "Review of drug safety and efficacy of arformoterol in chronic obstructive pulmonary disease". Expert Opinion on Drug Safety. 14 (3): 463–72. doi: 10.1517/14740338.2015.998196. PMID  25563342. S2CID  7767810.
  3. ^ "Competitive Generic Therapy Approvals". U.S. Food and Drug Administration (FDA). 29 June 2023. Archived from the original on 29 June 2023. Retrieved 29 June 2023.

External links



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