HS665 is a drug which acts as a potent and selective
κ-opioidreceptoragonist, and has
analgesic effects in animal studies.[1][2][3][4] HS665 is not an agonist for the mu receptor, leading to less potential for abuse.[5]
References
^Spetea M, Berzetei-Gurske IP, Guerrieri E, Schmidhammer H (November 2012). "Discovery and pharmacological evaluation of a diphenethylamine derivative (HS665), a highly potent and selective κ opioid receptor agonist". Journal of Medicinal Chemistry. 55 (22): 10302–10306.
doi:
10.1021/jm301258w.
PMID23134120.
^Advokat CD, Comaty JE, Julien RM (2019). Julien's Primer of Drug Action: A comprehensive guide to the actions, uses, and side effects of psychoactive drugs (14th ed.). New York: Worth Publishers. p. 564.
ISBN978-1-319-20054-1.
HS665 is a drug which acts as a potent and selective
κ-opioidreceptoragonist, and has
analgesic effects in animal studies.[1][2][3][4] HS665 is not an agonist for the mu receptor, leading to less potential for abuse.[5]
References
^Spetea M, Berzetei-Gurske IP, Guerrieri E, Schmidhammer H (November 2012). "Discovery and pharmacological evaluation of a diphenethylamine derivative (HS665), a highly potent and selective κ opioid receptor agonist". Journal of Medicinal Chemistry. 55 (22): 10302–10306.
doi:
10.1021/jm301258w.
PMID23134120.
^Advokat CD, Comaty JE, Julien RM (2019). Julien's Primer of Drug Action: A comprehensive guide to the actions, uses, and side effects of psychoactive drugs (14th ed.). New York: Worth Publishers. p. 564.
ISBN978-1-319-20054-1.