An enkephalinase inhibitor is a type of enzyme inhibitor which inhibits one or more members of the enkephalinase class of enzymes that break down the endogenous enkephalin opioid peptides. Examples include racecadotril, ubenimex (bestatin), RB-101, and D-phenylalanine, as well as the endogenous opioid peptides opiorphin and spinorphin. [1] It also includes RB-3007, Semax and Selank. Analgesic, anticraving, antidepressant, anxiolytic, and antidiarrheal effects are common properties of enkephalinase inhibitors. [1]
Rehydration | |
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Intestinal anti-infectives | |
Intestinal adsorbents |
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Antipropulsives ( opioids) |
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Intestinal anti-inflammatory agents |
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Antidiarrheal micro-organisms | |
Other antidiarrheals | |
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μ-opioid (MOR) |
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δ-opioid (DOR) |
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κ-opioid (KOR) |
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Nociceptin (NOP) |
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Others |
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An enkephalinase inhibitor is a type of enzyme inhibitor which inhibits one or more members of the enkephalinase class of enzymes that break down the endogenous enkephalin opioid peptides. Examples include racecadotril, ubenimex (bestatin), RB-101, and D-phenylalanine, as well as the endogenous opioid peptides opiorphin and spinorphin. [1] It also includes RB-3007, Semax and Selank. Analgesic, anticraving, antidepressant, anxiolytic, and antidiarrheal effects are common properties of enkephalinase inhibitors. [1]
Opioids |
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NSAIDs |
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Cannabinoids | |||||||||||||||||
Ion channel modulators |
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Myorelaxants | |||||||||||||||||
Others | |||||||||||||||||
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Rehydration | |
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Intestinal anti-infectives | |
Intestinal adsorbents |
|
Antipropulsives ( opioids) |
|
Intestinal anti-inflammatory agents |
|
Antidiarrheal micro-organisms | |
Other antidiarrheals | |
|
μ-opioid (MOR) |
| ||||
---|---|---|---|---|---|
δ-opioid (DOR) |
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κ-opioid (KOR) |
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Nociceptin (NOP) |
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Others |
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