Clinical data | |
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AHFS/ Drugs.com | International Drug Names |
Routes of administration | IV [1] [2] |
ATC code | |
Pharmacokinetic data | |
Elimination half-life | 2.4 hours [1] |
Excretion | Renal |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.060.336 |
Chemical and physical data | |
Formula | C14H20N2O3 |
Molar mass | 264.325 g·mol−1 |
3D model ( JSmol) | |
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| |
(verify) |
Propacetamol is a prodrug form of paracetamol which is formed from esterification of paracetamol, and the carboxylic acid diethylglycine. This has the advantage of making it more water-soluble. It is used in post-operative care and is delivered by I.V. [2] It is given if the patient is unable to take oral or rectally delivered paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated. The onset of analgesia from propacetamol is more rapid than paracetamol given orally. [3] 2 grams of propacetamol are equivalent to 1g of paracetamol. [4]
Clinical data | |
---|---|
AHFS/ Drugs.com | International Drug Names |
Routes of administration | IV [1] [2] |
ATC code | |
Pharmacokinetic data | |
Elimination half-life | 2.4 hours [1] |
Excretion | Renal |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.060.336 |
Chemical and physical data | |
Formula | C14H20N2O3 |
Molar mass | 264.325 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(verify) |
Propacetamol is a prodrug form of paracetamol which is formed from esterification of paracetamol, and the carboxylic acid diethylglycine. This has the advantage of making it more water-soluble. It is used in post-operative care and is delivered by I.V. [2] It is given if the patient is unable to take oral or rectally delivered paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated. The onset of analgesia from propacetamol is more rapid than paracetamol given orally. [3] 2 grams of propacetamol are equivalent to 1g of paracetamol. [4]