Names | |
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IUPAC name
(4R,4aS,7S,7aR,12bS)-9-methoxy-7-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-3-methyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-4a-ol
| |
Other names
Loxicodegol; NKTR-181
| |
Identifiers | |
3D model (
JSmol)
|
|
DrugBank | |
KEGG | |
PubChem
CID
|
|
UNII | |
| |
| |
Properties | |
C31H49NO10 | |
Molar mass | 595.730 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Oxycodegol (also known as loxicodegol and NKTR-181) is an experimental μ-opioid receptor agonist for the treatment of pain. [1] [2] It has had success for back pain as an alternative to traditional opioids, [3] which have potential for abuse. It acts more slowly on the central nervous system, reducing risk for abuse and respiratory depression. [1]
Names | |
---|---|
IUPAC name
(4R,4aS,7S,7aR,12bS)-9-methoxy-7-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-3-methyl-1,2,4,5,6,7,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-4a-ol
| |
Other names
Loxicodegol; NKTR-181
| |
Identifiers | |
3D model (
JSmol)
|
|
DrugBank | |
KEGG | |
PubChem
CID
|
|
UNII | |
| |
| |
Properties | |
C31H49NO10 | |
Molar mass | 595.730 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Oxycodegol (also known as loxicodegol and NKTR-181) is an experimental μ-opioid receptor agonist for the treatment of pain. [1] [2] It has had success for back pain as an alternative to traditional opioids, [3] which have potential for abuse. It acts more slowly on the central nervous system, reducing risk for abuse and respiratory depression. [1]