Names | |
---|---|
Other names
Dynorphin 1-13
| |
Identifiers | |
PubChem
CID
|
|
UNII | |
Properties | |
C75H126N24O15 | |
Molar mass | 1603.95474 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Dynorphin A is a dynorphin, an endogenous opioid peptide that activates the κ-opioid receptor. [2] Its amino acid sequence is Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys.
Dynorphin A1–8 is a truncated form of dynorphin A with the amino acid sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile. [3] [4] Dynorphin A1–8 is an agonist at the mu-, kappa-, and delta- opioid receptors; [4] it has the highest binding affinity for the kappa-opioid receptor. [4] Structures of dynorphin A bound to the κ-opioid receptor have been reported. [2] [5]
Principal endogenous agonists at κ receptor
Names | |
---|---|
Other names
Dynorphin 1-13
| |
Identifiers | |
PubChem
CID
|
|
UNII | |
Properties | |
C75H126N24O15 | |
Molar mass | 1603.95474 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Dynorphin A is a dynorphin, an endogenous opioid peptide that activates the κ-opioid receptor. [2] Its amino acid sequence is Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys.
Dynorphin A1–8 is a truncated form of dynorphin A with the amino acid sequence: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile. [3] [4] Dynorphin A1–8 is an agonist at the mu-, kappa-, and delta- opioid receptors; [4] it has the highest binding affinity for the kappa-opioid receptor. [4] Structures of dynorphin A bound to the κ-opioid receptor have been reported. [2] [5]
Principal endogenous agonists at κ receptor