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Formula | C21H25NO4 |
Molar mass | 355.434 g·mol−1 |
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Nalmexone ( INN) (code names EN-1620A, UM-592), or nalmexone hydrochloride ( USAN), is a semisynthetic, opioid partial agonist or mixed agonist- antagonist with both analgesic and narcotic antagonist properties that was never marketed. [1] [2] [3] [4] In clinical studies it was found to have comparable analgesic efficacy to morphine, though with several-fold reduced potency. [5] In addition, nalmexone's side effects, the most common of which were sleepiness and sweating, were reported to be similar to those of morphine, albeit with a noticeably higher degree of incidence. [5]
Clinical data | |
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ATC code |
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Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C21H25NO4 |
Molar mass | 355.434 g·mol−1 |
3D model ( JSmol) | |
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Nalmexone ( INN) (code names EN-1620A, UM-592), or nalmexone hydrochloride ( USAN), is a semisynthetic, opioid partial agonist or mixed agonist- antagonist with both analgesic and narcotic antagonist properties that was never marketed. [1] [2] [3] [4] In clinical studies it was found to have comparable analgesic efficacy to morphine, though with several-fold reduced potency. [5] In addition, nalmexone's side effects, the most common of which were sleepiness and sweating, were reported to be similar to those of morphine, albeit with a noticeably higher degree of incidence. [5]