Names | |
---|---|
Preferred IUPAC name
Benzyl [(2S)-3-(acetylsulfanyl)-2-benzylpropanamido]acetate | |
Identifiers | |
3D model (
JSmol)
|
|
ChEMBL | |
ChemSpider | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C21H23NO4S | |
Molar mass | 385.48 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Ecadotril is a neutral endopeptidase inhibitor ((NEP [1]) EC 3.4.24.11 [2]) and determined by the presence of peptidase family M13 as a neutral endopeptidase inhibited by phosphoramidon. Ecadotril is the (S)- enantiomer of racecadotril. NEP-like enzymes include the endothelin- converting enzymes. [3] The peptidase M13 family believed to activate or inactivate oligopeptide (pro)-hormones such as opioid peptides, [3] neprilysin [3] is another member of this group, in the case of the metallopeptidases and aspartic, the nucleophiles clan or family for example MA, is an activated water molecule. [1] The peptidase domain for members of this family also contains a bacterial member and resembles that of thermolysin the predicted active site residues for members of this family and thermolysin occur in the motif HEXXH. [4] Thermolysin complexed with the inhibitor (S)- thiorphan are isomeric thiol-containing inhibitors of endopeptidase EC 24-11 [5] (also called " enkephalinase").
Names | |
---|---|
Preferred IUPAC name
Benzyl [(2S)-3-(acetylsulfanyl)-2-benzylpropanamido]acetate | |
Identifiers | |
3D model (
JSmol)
|
|
ChEMBL | |
ChemSpider | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C21H23NO4S | |
Molar mass | 385.48 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Ecadotril is a neutral endopeptidase inhibitor ((NEP [1]) EC 3.4.24.11 [2]) and determined by the presence of peptidase family M13 as a neutral endopeptidase inhibited by phosphoramidon. Ecadotril is the (S)- enantiomer of racecadotril. NEP-like enzymes include the endothelin- converting enzymes. [3] The peptidase M13 family believed to activate or inactivate oligopeptide (pro)-hormones such as opioid peptides, [3] neprilysin [3] is another member of this group, in the case of the metallopeptidases and aspartic, the nucleophiles clan or family for example MA, is an activated water molecule. [1] The peptidase domain for members of this family also contains a bacterial member and resembles that of thermolysin the predicted active site residues for members of this family and thermolysin occur in the motif HEXXH. [4] Thermolysin complexed with the inhibitor (S)- thiorphan are isomeric thiol-containing inhibitors of endopeptidase EC 24-11 [5] (also called " enkephalinase").