The testicular receptor 2 (TR2) also known as NR2C1 (nuclear receptor subfamily 2, group C, member 1) is
protein that in humans is encoded by the NR2C1gene.[5][6] TR2 is a member of the
nuclear receptor family of
transcription factors.
Interactions
Testicular receptor 2 has been shown to
interact with:
^Chang C, Kokontis J, Acakpo-Satchivi L, Liao S, Takeda H, Chang Y (Dec 1989). "Molecular cloning of new human TR2 receptors: a class of steroid receptor with multiple ligand-binding domains". Biochemical and Biophysical Research Communications. 165 (2): 735–41.
doi:
10.1016/S0006-291X(89)80028-2.
PMID2597158.
^Mu X, Chang C (Oct 2003). "TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3". The Prostate. 57 (2): 129–33.
doi:
10.1002/pros.10282.
PMID12949936.
S2CID24134119.
Chang C, Kokontis J (Sep 1988). "Identification of a new member of the steroid receptor super-family by cloning and sequence analysis". Biochemical and Biophysical Research Communications. 155 (2): 971–7.
doi:
10.1016/S0006-291X(88)80591-6.
PMID3421977.
Lin DL, Wu SQ, Chang C (Apr 1998). "The genomic structure and chromosomal location of the human TR2 orphan receptor, a member of the steroid receptor superfamily". Endocrine. 8 (2): 123–34.
doi:
10.1385/ENDO:8:2:123.
PMID9704569.
S2CID23712655.
Inui S, Lee YF, Chang E, Shyr CR, Chang C (Feb 2003). "Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes". Journal of Dermatological Science. 31 (1): 65–71.
doi:
10.1016/S0923-1811(02)00152-4.
PMID12615366.
Franco PJ, Li G, Wei LN (Aug 2003). "Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase". Molecular and Cellular Endocrinology. 206 (1–2): 1–12.
doi:
10.1016/S0303-7207(03)00254-5.
PMID12943985.
S2CID19487189.
Mu X, Chang C (Oct 2003). "TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3". The Prostate. 57 (2): 129–33.
doi:
10.1002/pros.10282.
PMID12949936.
S2CID24134119.
Li G, Franco PJ, Wei LN (Oct 2003). "Identification of histone deacetylase-3 domains that interact with the orphan nuclear receptor TR2". Biochemical and Biophysical Research Communications. 310 (2): 384–90.
doi:
10.1016/j.bbrc.2003.08.145.
PMID14521922.
Lin YL, Wang YH, Lee HJ (Nov 2006). "Transcriptional regulation of the human TR2 orphan receptor gene by nuclear factor 1-A". Biochemical and Biophysical Research Communications. 350 (2): 430–6.
doi:
10.1016/j.bbrc.2006.09.061.
PMID17010934.
The testicular receptor 2 (TR2) also known as NR2C1 (nuclear receptor subfamily 2, group C, member 1) is
protein that in humans is encoded by the NR2C1gene.[5][6] TR2 is a member of the
nuclear receptor family of
transcription factors.
Interactions
Testicular receptor 2 has been shown to
interact with:
^Chang C, Kokontis J, Acakpo-Satchivi L, Liao S, Takeda H, Chang Y (Dec 1989). "Molecular cloning of new human TR2 receptors: a class of steroid receptor with multiple ligand-binding domains". Biochemical and Biophysical Research Communications. 165 (2): 735–41.
doi:
10.1016/S0006-291X(89)80028-2.
PMID2597158.
^Mu X, Chang C (Oct 2003). "TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3". The Prostate. 57 (2): 129–33.
doi:
10.1002/pros.10282.
PMID12949936.
S2CID24134119.
Chang C, Kokontis J (Sep 1988). "Identification of a new member of the steroid receptor super-family by cloning and sequence analysis". Biochemical and Biophysical Research Communications. 155 (2): 971–7.
doi:
10.1016/S0006-291X(88)80591-6.
PMID3421977.
Lin DL, Wu SQ, Chang C (Apr 1998). "The genomic structure and chromosomal location of the human TR2 orphan receptor, a member of the steroid receptor superfamily". Endocrine. 8 (2): 123–34.
doi:
10.1385/ENDO:8:2:123.
PMID9704569.
S2CID23712655.
Inui S, Lee YF, Chang E, Shyr CR, Chang C (Feb 2003). "Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes". Journal of Dermatological Science. 31 (1): 65–71.
doi:
10.1016/S0923-1811(02)00152-4.
PMID12615366.
Franco PJ, Li G, Wei LN (Aug 2003). "Interaction of nuclear receptor zinc finger DNA binding domains with histone deacetylase". Molecular and Cellular Endocrinology. 206 (1–2): 1–12.
doi:
10.1016/S0303-7207(03)00254-5.
PMID12943985.
S2CID19487189.
Mu X, Chang C (Oct 2003). "TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3". The Prostate. 57 (2): 129–33.
doi:
10.1002/pros.10282.
PMID12949936.
S2CID24134119.
Li G, Franco PJ, Wei LN (Oct 2003). "Identification of histone deacetylase-3 domains that interact with the orphan nuclear receptor TR2". Biochemical and Biophysical Research Communications. 310 (2): 384–90.
doi:
10.1016/j.bbrc.2003.08.145.
PMID14521922.
Lin YL, Wang YH, Lee HJ (Nov 2006). "Transcriptional regulation of the human TR2 orphan receptor gene by nuclear factor 1-A". Biochemical and Biophysical Research Communications. 350 (2): 430–6.
doi:
10.1016/j.bbrc.2006.09.061.
PMID17010934.
