Transcription factor RFX4 is a
protein that in humans is encoded by the RFX4gene.[5][6][7]
This gene is a member of the regulatory factor X gene family, which encodes
transcription factors that contain a highly conserved winged helix DNA
binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional
repressor rather than a transcriptional activator. Three transcript variants encoding different
isoforms have been described for this gene.[7]
Transcription factor RFX4 is a
protein that in humans is encoded by the RFX4gene.[5][6][7]
This gene is a member of the regulatory factor X gene family, which encodes
transcription factors that contain a highly conserved winged helix DNA
binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional
repressor rather than a transcriptional activator. Three transcript variants encoding different
isoforms have been described for this gene.[7]