CCAAT/enhancer-binding protein gamma (C/EBPγ) is a
protein that in humans is encoded by the CEBPGgene.[5][6] This gene has no
introns.
The
C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the
bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a
leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins,
C/EBPα,
C/EBPβ, C/EBPγ,
C/EBPδ,
C/EBPζ, and
C/EBPε, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with
Fos to bind the positive regulatory element-I (PRE-I) enhancer elements.[6][7]
Nishizawa M, Nagata S (1992). "cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein". FEBS Lett. 299 (1): 36–8.
doi:
10.1016/0014-5793(92)80094-W.
PMID1371974.
S2CID34097395.
Lundgren M, Larsson C, Femino A, et al. (1994). "Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site". J. Immunol. 153 (7): 2983–95.
doi:
10.4049/jimmunol.153.7.2983.
PMID8089482.
S2CID24982598.
Hattori T, Ohoka N, Inoue Y, et al. (2003). "C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer". Oncogene. 22 (9): 1273–80.
doi:
10.1038/sj.onc.1206204.
PMID12618752.
S2CID1351748.
CCAAT/enhancer-binding protein gamma (C/EBPγ) is a
protein that in humans is encoded by the CEBPGgene.[5][6] This gene has no
introns.
The
C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the
bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a
leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins,
C/EBPα,
C/EBPβ, C/EBPγ,
C/EBPδ,
C/EBPζ, and
C/EBPε, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with
Fos to bind the positive regulatory element-I (PRE-I) enhancer elements.[6][7]
Nishizawa M, Nagata S (1992). "cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein". FEBS Lett. 299 (1): 36–8.
doi:
10.1016/0014-5793(92)80094-W.
PMID1371974.
S2CID34097395.
Lundgren M, Larsson C, Femino A, et al. (1994). "Activation of the Ig germ-line gamma 1 promoter. Involvement of C/enhancer-binding protein transcription factors and their possible interaction with an NF-IL-4 site". J. Immunol. 153 (7): 2983–95.
doi:
10.4049/jimmunol.153.7.2983.
PMID8089482.
S2CID24982598.
Hattori T, Ohoka N, Inoue Y, et al. (2003). "C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer". Oncogene. 22 (9): 1273–80.
doi:
10.1038/sj.onc.1206204.
PMID12618752.
S2CID1351748.