Transcription cofactor HES-6 is a protein that in humans is encoded by the HES6 gene. [5] [6]
Interactions
HES6 has been shown to interact with TLE1. [7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000144485 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067071 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Bae S, Bessho Y, Hojo M, Kageyama R (Aug 2000). "The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation". Development. 127 (13): 2933–43. doi: 10.1242/dev.127.13.2933. PMID 10851137.
- ^ "Entrez Gene: HES6 hairy and enhancer of split 6 (Drosophila)".
- ^ Gao X, Chandra T, Gratton MO, Quélo I, Prud'homme J, Stifani S, St-Arnaud R (Sep 2001). "HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program". J. Cell Biol. 154 (6): 1161–71. doi: 10.1083/jcb.200104058. PMC 2150829. PMID 11551980.
Further reading
- Bech P, Bolwig TG, Dein E, Jacobsen O, Gram LF (1975). "Quantitative rating of manic states. Correlation between clinical assessment and Biegel's Objective Rating Scale". Acta Psychiatr Scand. 52 (1): 1–6. doi: 10.1111/j.1600-0447.1975.tb00017.x. PMID 1155198. S2CID 7793095.
- Vasiliauskas D, Stern CD (2000). "Expression of mouse HES-6, a new member of the Hairy/Enhancer of split family of bHLH transcription factors". Mech. Dev. 98 (1–2): 133–7. doi: 10.1016/S0925-4773(00)00443-3. PMID 11044617. S2CID 15528953.
- Gao X, Chandra T, Gratton MO, Quélo I, Prud'homme J, Stifani S, St-Arnaud R (2001). "HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program". J. Cell Biol. 154 (6): 1161–71. doi: 10.1083/jcb.200104058. PMC 2150829. PMID 11551980.
- Swearingen ML, Sun D, Bourner M, Weinstein EJ (2003). "Detection of differentially expressed HES-6 gene in metastatic colon carcinoma by combination of suppression subtractive hybridization and cDNA library array". Cancer Lett. 198 (2): 229–39. doi: 10.1016/S0304-3835(03)00313-6. PMID 12957362.
- Gratton MO, Torban E, Jasmin SB, Theriault FM, German MS, Stifani S (2003). "Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms". Mol. Cell. Biol. 23 (19): 6922–35. doi: 10.1128/MCB.23.19.6922-6935.2003. PMC 193938. PMID 12972610.
- Kang SA, Seol JH, Kim J (2005). "The conserved WRPW motif of Hes6 mediates proteasomal degradation". Biochem. Biophys. Res. Commun. 332 (1): 33–6. doi: 10.1016/j.bbrc.2005.04.089. PMID 15896295.
- Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F (2007). "HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion". Biochem. Biophys. Res. Commun. 355 (2): 331–7. doi: 10.1016/j.bbrc.2007.01.153. PMC 1852427. PMID 17300753.
- Carey KA, Farnfield MM, Tarquinio SD, Cameron-Smith D (2007). "Impaired expression of Notch signaling genes in aged human skeletal muscle". J. Gerontol. A Biol. Sci. Med. Sci. 62 (1): 9–17. CiteSeerX 10.1.1.499.7911. doi: 10.1093/gerona/62.1.9. PMID 17301032.
- Scheffer D, Sage C, Corey DP, Pingault V (2007). "Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells". FEBS Lett. 581 (24): 4651–6. doi: 10.1016/j.febslet.2007.08.059. PMID 17826772. S2CID 13986512.
External links
- HES6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
 | This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it. |
| HES6 | |||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | HES6, C-HAIRY1, HES-6, bHLHb41, bHLHc23, hes family bHLH transcription factor 6 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 610331; MGI: 1859852; HomoloGene: 23111; GeneCards: HES6; OMA: HES6 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
Transcription cofactor HES-6 is a protein that in humans is encoded by the HES6 gene. [5] [6]
Interactions
HES6 has been shown to interact with TLE1. [7]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000144485 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000067071 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Bae S, Bessho Y, Hojo M, Kageyama R (Aug 2000). "The bHLH gene Hes6, an inhibitor of Hes1, promotes neuronal differentiation". Development. 127 (13): 2933–43. doi: 10.1242/dev.127.13.2933. PMID 10851137.
- ^ "Entrez Gene: HES6 hairy and enhancer of split 6 (Drosophila)".
- ^ Gao X, Chandra T, Gratton MO, Quélo I, Prud'homme J, Stifani S, St-Arnaud R (Sep 2001). "HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program". J. Cell Biol. 154 (6): 1161–71. doi: 10.1083/jcb.200104058. PMC 2150829. PMID 11551980.
Further reading
- Bech P, Bolwig TG, Dein E, Jacobsen O, Gram LF (1975). "Quantitative rating of manic states. Correlation between clinical assessment and Biegel's Objective Rating Scale". Acta Psychiatr Scand. 52 (1): 1–6. doi: 10.1111/j.1600-0447.1975.tb00017.x. PMID 1155198. S2CID 7793095.
- Vasiliauskas D, Stern CD (2000). "Expression of mouse HES-6, a new member of the Hairy/Enhancer of split family of bHLH transcription factors". Mech. Dev. 98 (1–2): 133–7. doi: 10.1016/S0925-4773(00)00443-3. PMID 11044617. S2CID 15528953.
- Gao X, Chandra T, Gratton MO, Quélo I, Prud'homme J, Stifani S, St-Arnaud R (2001). "HES6 acts as a transcriptional repressor in myoblasts and can induce the myogenic differentiation program". J. Cell Biol. 154 (6): 1161–71. doi: 10.1083/jcb.200104058. PMC 2150829. PMID 11551980.
- Swearingen ML, Sun D, Bourner M, Weinstein EJ (2003). "Detection of differentially expressed HES-6 gene in metastatic colon carcinoma by combination of suppression subtractive hybridization and cDNA library array". Cancer Lett. 198 (2): 229–39. doi: 10.1016/S0304-3835(03)00313-6. PMID 12957362.
- Gratton MO, Torban E, Jasmin SB, Theriault FM, German MS, Stifani S (2003). "Hes6 promotes cortical neurogenesis and inhibits Hes1 transcription repression activity by multiple mechanisms". Mol. Cell. Biol. 23 (19): 6922–35. doi: 10.1128/MCB.23.19.6922-6935.2003. PMC 193938. PMID 12972610.
- Kang SA, Seol JH, Kim J (2005). "The conserved WRPW motif of Hes6 mediates proteasomal degradation". Biochem. Biophys. Res. Commun. 332 (1): 33–6. doi: 10.1016/j.bbrc.2005.04.089. PMID 15896295.
- Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F (2007). "HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion". Biochem. Biophys. Res. Commun. 355 (2): 331–7. doi: 10.1016/j.bbrc.2007.01.153. PMC 1852427. PMID 17300753.
- Carey KA, Farnfield MM, Tarquinio SD, Cameron-Smith D (2007). "Impaired expression of Notch signaling genes in aged human skeletal muscle". J. Gerontol. A Biol. Sci. Med. Sci. 62 (1): 9–17. CiteSeerX 10.1.1.499.7911. doi: 10.1093/gerona/62.1.9. PMID 17301032.
- Scheffer D, Sage C, Corey DP, Pingault V (2007). "Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells". FEBS Lett. 581 (24): 4651–6. doi: 10.1016/j.febslet.2007.08.059. PMID 17826772. S2CID 13986512.
External links
- HES6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
|
| This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it. |