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From Wikipedia, the free encyclopedia
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Identifiers
Symbol TFAP2A
Alt. symbolsTFAP2, AP2TF
NCBI gene 7020
HGNC 11742
OMIM 107580
RefSeq NM_003220
UniProt P05549
Other data
Locus Chr. 6 p22.3
Search for
Structures Swiss-model
Domains InterPro
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Identifiers
SymbolTFAP2B
Alt. symbolsAP2-B
NCBI gene 7021
HGNC 11743
OMIM 601601
RefSeq NM_003221
UniProt Q92481
Other data
Locus Chr. 6 p12
Search for
Structures Swiss-model
Domains InterPro
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Identifiers
SymbolTFAP2C
NCBI gene 7022
HGNC 11744
OMIM 601602
RefSeq NM_003222
UniProt Q92754
Other data
Locus Chr. 20 q13.2
Search for
Structures Swiss-model
Domains InterPro
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
Identifiers
SymbolTFAP2D
Alt. symbolsTFAP2BL1
NCBI gene 83741
HGNC 15581
OMIM 610161
RefSeq NM_172238
UniProt Q7Z6R9
Other data
Locus Chr. 6 p12.3
Search for
Structures Swiss-model
Domains InterPro
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
Identifiers
SymbolTFAP2E
Alt. symbolsAP2E
NCBI gene 339488
HGNC 30774
RefSeq NM_178548
UniProt Q6VUC0
Other data
Locus Chr. 1 p34.3
Search for
Structures Swiss-model
Domains InterPro

Activating Protein 2 (AP-2) is a family of closely related transcription factors [1] [2] which plays a critical role in regulating gene expression during early development. [3]

References

  1. ^ Williams T, Tjian R (1991). "Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins". Science. 251 (4997): 1067–71. Bibcode: 1991Sci...251.1067W. doi: 10.1126/science.1998122. PMID  1998122.
  2. ^ Williams T, Tjian R (1991). "Analysis of the DNA-binding and activation properties of the human transcription factor AP-2". Genes Dev. 5 (4): 670–82. doi: 10.1101/gad.5.4.670. PMID  2010091.
  3. ^ Hilger-Eversheim K, Moser M, Schorle H, Buettner R (2000). "Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control". Gene. 260 (1–2): 1–12. doi: 10.1016/S0378-1119(00)00454-6. PMID  11137286.

External links


Stub icon

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

Retrieved from " https://en.wikipedia.org/?title=Activating_protein_2&oldid=1075850008"
From Wikipedia, the free encyclopedia
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
Identifiers
Symbol TFAP2A
Alt. symbolsTFAP2, AP2TF
NCBI gene 7020
HGNC 11742
OMIM 107580
RefSeq NM_003220
UniProt P05549
Other data
Locus Chr. 6 p22.3
Search for
Structures Swiss-model
Domains InterPro
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Identifiers
SymbolTFAP2B
Alt. symbolsAP2-B
NCBI gene 7021
HGNC 11743
OMIM 601601
RefSeq NM_003221
UniProt Q92481
Other data
Locus Chr. 6 p12
Search for
Structures Swiss-model
Domains InterPro
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
Identifiers
SymbolTFAP2C
NCBI gene 7022
HGNC 11744
OMIM 601602
RefSeq NM_003222
UniProt Q92754
Other data
Locus Chr. 20 q13.2
Search for
Structures Swiss-model
Domains InterPro
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
Identifiers
SymbolTFAP2D
Alt. symbolsTFAP2BL1
NCBI gene 83741
HGNC 15581
OMIM 610161
RefSeq NM_172238
UniProt Q7Z6R9
Other data
Locus Chr. 6 p12.3
Search for
Structures Swiss-model
Domains InterPro
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
Identifiers
SymbolTFAP2E
Alt. symbolsAP2E
NCBI gene 339488
HGNC 30774
RefSeq NM_178548
UniProt Q6VUC0
Other data
Locus Chr. 1 p34.3
Search for
Structures Swiss-model
Domains InterPro

Activating Protein 2 (AP-2) is a family of closely related transcription factors [1] [2] which plays a critical role in regulating gene expression during early development. [3]

References

  1. ^ Williams T, Tjian R (1991). "Characterization of a dimerization motif in AP-2 and its function in heterologous DNA-binding proteins". Science. 251 (4997): 1067–71. Bibcode: 1991Sci...251.1067W. doi: 10.1126/science.1998122. PMID  1998122.
  2. ^ Williams T, Tjian R (1991). "Analysis of the DNA-binding and activation properties of the human transcription factor AP-2". Genes Dev. 5 (4): 670–82. doi: 10.1101/gad.5.4.670. PMID  2010091.
  3. ^ Hilger-Eversheim K, Moser M, Schorle H, Buettner R (2000). "Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control". Gene. 260 (1–2): 1–12. doi: 10.1016/S0378-1119(00)00454-6. PMID  11137286.

External links


Stub icon

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

Retrieved from " https://en.wikipedia.org/?title=Activating_protein_2&oldid=1075850008"

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