From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Zing finger protein 644 (ZNF644) also known as zinc finger motif enhancer-binding protein 2 (Zep-2) is a
protein that in humans is encoded by the ZNF644
gene .
[5]
Clinical relevance
Mutations in the ZNF644 gene have been found in sporadic cases of high
myopia .
[6]
References
Further reading
Zabaneh D, Balding DJ (2010).
"A genome-wide association study of the metabolic syndrome in Indian Asian men" . PLOS ONE . 5 (8): e11961.
Bibcode :
2010PLoSO...511961Z .
doi :
10.1371/journal.pone.0011961 .
PMC
2915922 .
PMID
20694148 .
Mulligan P, Westbrook TF, Ottinger M, et al. (2008).
"CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation" . Mol. Cell . 32 (5): 718–26.
doi :
10.1016/j.molcel.2008.10.025 .
PMC
6595072 .
PMID
19061646 .
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004).
"Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proc. Natl. Acad. Sci. U.S.A . 101 (33): 12130–5.
Bibcode :
2004PNAS..10112130B .
doi :
10.1073/pnas.0404720101 .
PMC
514446 .
PMID
15302935 .
Gregory SG, Barlow KF, McLay KE, et al. (2006).
"The DNA sequence and biological annotation of human chromosome 1" . Nature . 441 (7091): 315–21.
Bibcode :
2006Natur.441..315G .
doi :
10.1038/nature04727 .
PMID
16710414 .
Zhang QH, Ye M, Wu XY, et al. (2000).
"Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells" . Genome Res . 10 (10): 1546–60.
doi :
10.1101/gr.140200 .
PMC
310934 .
PMID
11042152 .
(1) Basic domains
(1.1) Basic
leucine zipper (
bZIP )(1.2) Basic helix-loop-helix (
bHLH )
Group A Group B Group C bHLH-
PAS Group D Group E Group F bHLH-COE
(1.3)
bHLH-ZIP (1.4) NF-1 (1.5) RF-X (1.6) Basic helix-span-helix (bHSH)
(2)
Zinc finger DNA-binding domains
(2.1)
Nuclear receptor (Cys4 )
subfamily 1 subfamily 2 subfamily 3 subfamily 4 subfamily 5 subfamily 6 subfamily 0
(2.2) Other Cys4 (2.3) Cys2 His2 (2.4) Cys6 (2.5) Alternating composition (2.6) WRKY
(4) β-Scaffold factors with minor groove contacts
(0) Other transcription factors