Nuclear factor, interleukin 3 regulated, also known as NFIL3 or E4BP4 is a
protein which in humans is encoded by the NFIL3gene.[5]
Function
Expression of interleukin-3 (
IL-3) is restricted to activated
T cells, natural killer (
NK) cells, and
mast cell lines.
Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site.[5][6]
Matoba R, Okubo K, Hori N, Fukushima A, Matsubara K (September 1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199–207.
doi:
10.1016/0378-1119(94)90293-3.
PMID8076819.
Hulme DJ, Blair IP, Dawkins JL, Nicholson GA (June 2000). "Exclusion of NFIL3 as the gene causing hereditary sensory neuropathy type I by mutation analysis". Human Genetics. 106 (6): 594–6.
doi:
10.1007/s004390000306.
PMID10942106.
Nuclear factor, interleukin 3 regulated, also known as NFIL3 or E4BP4 is a
protein which in humans is encoded by the NFIL3gene.[5]
Function
Expression of interleukin-3 (
IL-3) is restricted to activated
T cells, natural killer (
NK) cells, and
mast cell lines.
Transcription initiation depends on the activating capacity of specific protein factors, such as NFIL3, that bind to regulatory regions of the gene, usually upstream of the transcription start site.[5][6]
Matoba R, Okubo K, Hori N, Fukushima A, Matsubara K (September 1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199–207.
doi:
10.1016/0378-1119(94)90293-3.
PMID8076819.
Hulme DJ, Blair IP, Dawkins JL, Nicholson GA (June 2000). "Exclusion of NFIL3 as the gene causing hereditary sensory neuropathy type I by mutation analysis". Human Genetics. 106 (6): 594–6.
doi:
10.1007/s004390000306.
PMID10942106.