Names | |
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Preferred IUPAC name
2-Acetamido-5-amino-5-oxopentanoic acid | |
Other names | |
Identifiers | |
| |
3D model (
JSmol)
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ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.017.862 |
EC Number |
|
KEGG | |
MeSH | aceglutamide |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C7H12N2O4 | |
Molar mass | 188.183 g·mol−1 |
Appearance | White crystals |
Melting point | 197 °C (387 °F; 470 K) |
Related compounds | |
Related alkanoic acids
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Related compounds
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Aceglutamide (brand name Neuramina), or aceglutamide aluminium (brand name Glumal), also known as acetylglutamine, is a psychostimulant, nootropic, and antiulcer agent that is marketed in Spain and Japan. [1] [2] [3] [4] It is an acetylated form of the amino acid L-glutamine, the precursor of glutamate in the body and brain. [5] Aceglutamide functions as a prodrug to glutamine with improved potency and stability. [5]
Aceglutamide is used as a psychostimulant and nootropic, while aceglutamide aluminium is used in the treatment of ulcers. [6] [7] [8] [9] Aceglutamide can also be used as a liquid-stable source of glutamine to prevent damage from protein energy malnutrition. [10] [11] [12] The drug has shown neuroprotective effects in an animal model of cerebral ischemia. [5]
Names | |
---|---|
Preferred IUPAC name
2-Acetamido-5-amino-5-oxopentanoic acid | |
Other names | |
Identifiers | |
| |
3D model (
JSmol)
|
|
ChemSpider | |
DrugBank | |
ECHA InfoCard | 100.017.862 |
EC Number |
|
KEGG | |
MeSH | aceglutamide |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C7H12N2O4 | |
Molar mass | 188.183 g·mol−1 |
Appearance | White crystals |
Melting point | 197 °C (387 °F; 470 K) |
Related compounds | |
Related alkanoic acids
|
|
Related compounds
|
|
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Aceglutamide (brand name Neuramina), or aceglutamide aluminium (brand name Glumal), also known as acetylglutamine, is a psychostimulant, nootropic, and antiulcer agent that is marketed in Spain and Japan. [1] [2] [3] [4] It is an acetylated form of the amino acid L-glutamine, the precursor of glutamate in the body and brain. [5] Aceglutamide functions as a prodrug to glutamine with improved potency and stability. [5]
Aceglutamide is used as a psychostimulant and nootropic, while aceglutamide aluminium is used in the treatment of ulcers. [6] [7] [8] [9] Aceglutamide can also be used as a liquid-stable source of glutamine to prevent damage from protein energy malnutrition. [10] [11] [12] The drug has shown neuroprotective effects in an animal model of cerebral ischemia. [5]