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| Identifiers | |
|---|---|
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| CompTox Dashboard ( EPA) | |
| Chemical and physical data | |
| Formula | C19H19N3O3 |
| Molar mass | 337.379 g·mol−1 |
| 3D model ( JSmol) | |
| |
| (verify) | |
MMPIP is a drug used in scientific research that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR7. [1] This receptor subtype appears to be involved in the downstream response to cocaine in the brain. [2]
References
- ^ Suzuki G, Tsukamoto N, Fushiki H, Kawagishi A, Nakamura M, Kurihara H, Mitsuya M, Ohkubo M, Ohta H (October 2007). "In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists". The Journal of Pharmacology and Experimental Therapeutics. 323 (1): 147–56. doi: 10.1124/jpet.107.124701. PMID 17609420. S2CID 10402176.
- ^ Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX (June 2009). "Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism". Neuropsychopharmacology. 34 (7): 1783–96. doi: 10.1038/npp.2008.236. PMC 3739975. PMID 19158667.
 | This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |
|
| |
| Identifiers | |
|---|---|
| |
| CompTox Dashboard ( EPA) | |
| Chemical and physical data | |
| Formula | C19H19N3O3 |
| Molar mass | 337.379 g·mol−1 |
| 3D model ( JSmol) | |
| |
| (verify) | |
MMPIP is a drug used in scientific research that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR7. [1] This receptor subtype appears to be involved in the downstream response to cocaine in the brain. [2]
References
- ^ Suzuki G, Tsukamoto N, Fushiki H, Kawagishi A, Nakamura M, Kurihara H, Mitsuya M, Ohkubo M, Ohta H (October 2007). "In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists". The Journal of Pharmacology and Experimental Therapeutics. 323 (1): 147–56. doi: 10.1124/jpet.107.124701. PMID 17609420. S2CID 10402176.
- ^ Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX (June 2009). "Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism". Neuropsychopharmacology. 34 (7): 1783–96. doi: 10.1038/npp.2008.236. PMC 3739975. PMID 19158667.
|
| This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |