Clinical data | |
---|---|
Other names | L-2-Amino-4-phosphonobutyric acid |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
IUPHAR/BPS | |
ChemSpider | |
UNII | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.164.384 |
Chemical and physical data | |
Formula | C4H10NO5P |
Molar mass | 183.100 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(what is this?) (verify) |
L-AP4 (L-2-amino-4-phosphonobutyric acid) is a drug used in scientific research, which acts as a group-selective agonist for the group III metabotropic glutamate receptors ( mGluR4/ 6/ 7/ 8). It was the first ligand found to act as an agonist selective for this group of mGlu receptors, [1] but does not show selectivity between the different mGluR Group III subtypes. It is widely used in the study of this receptor family and their various functions. [2] [3] [4] [5]
Clinical data | |
---|---|
Other names | L-2-Amino-4-phosphonobutyric acid |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
IUPHAR/BPS | |
ChemSpider | |
UNII | |
CompTox Dashboard ( EPA) | |
ECHA InfoCard | 100.164.384 |
Chemical and physical data | |
Formula | C4H10NO5P |
Molar mass | 183.100 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(what is this?) (verify) |
L-AP4 (L-2-amino-4-phosphonobutyric acid) is a drug used in scientific research, which acts as a group-selective agonist for the group III metabotropic glutamate receptors ( mGluR4/ 6/ 7/ 8). It was the first ligand found to act as an agonist selective for this group of mGlu receptors, [1] but does not show selectivity between the different mGluR Group III subtypes. It is widely used in the study of this receptor family and their various functions. [2] [3] [4] [5]