5,7-Dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one (DMPC) is a derivative of
oroxylin A. It has memory improving effects and can reduce ADHD-like behavior.
Mechanism of action
As a derivative of oroxylin A, it has similar activity; in rats, DMPC has been shown to
block the reuptake of dopamine similarly to
methylphenidate, however it does not act at the
norepinephrine transporter. This has resulted in attenuated ADHD-like behavior, but unlike
methylphenidate and other ADHD medication, it did not display addictive properties. Which could make it useful as a non-addictive ADHD drugs, as most currently used ADHD stimulants have addictive properties.[3]
DMPC also possesses memory improving properties, it is able to attenuate memory impairment induced by
scopolamine and
MK-801. It also had memory-enhancing effects if administered alone.[4]
5,7-Dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one (DMPC) is a derivative of
oroxylin A. It has memory improving effects and can reduce ADHD-like behavior.
Mechanism of action
As a derivative of oroxylin A, it has similar activity; in rats, DMPC has been shown to
block the reuptake of dopamine similarly to
methylphenidate, however it does not act at the
norepinephrine transporter. This has resulted in attenuated ADHD-like behavior, but unlike
methylphenidate and other ADHD medication, it did not display addictive properties. Which could make it useful as a non-addictive ADHD drugs, as most currently used ADHD stimulants have addictive properties.[3]
DMPC also possesses memory improving properties, it is able to attenuate memory impairment induced by
scopolamine and
MK-801. It also had memory-enhancing effects if administered alone.[4]