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CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C31H39NO4 |
Molar mass | 489.656 g·mol−1 |
3D model ( JSmol) | |
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(what is this?) (verify) |
7-PET is an opioid analgesic drug that has 300 times the potency of morphine by weight. [1] It was discovered by K.W. Bentley [2] and is related to the more well known oripavine derivative etorphine, which is used as a veterinary painkiller and anesthetic medication for the sedation of large animals such as elephants, giraffes, and rhinos. 7-PET itself has a 3-O-methyl ether which reduces potency, but the 3-OH derivative is around 2200 times more potent than morphine, almost the same potency as etorphine as a μ agonist, [3] [4] and unexpectedly the 3-hydrogen compound is also around the same potency of 2000 times morphine. [5]
Unlike etorphine, 7-PET is not controlled under the UN drug conventions, but it might still be considered to be a controlled substance analogue of etorphine on the grounds of its related chemical structure in some jurisdictions such as the United States, Canada, Australia, and New Zealand.
Identifiers | |
---|---|
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard ( EPA) | |
Chemical and physical data | |
Formula | C31H39NO4 |
Molar mass | 489.656 g·mol−1 |
3D model ( JSmol) | |
| |
| |
(what is this?) (verify) |
7-PET is an opioid analgesic drug that has 300 times the potency of morphine by weight. [1] It was discovered by K.W. Bentley [2] and is related to the more well known oripavine derivative etorphine, which is used as a veterinary painkiller and anesthetic medication for the sedation of large animals such as elephants, giraffes, and rhinos. 7-PET itself has a 3-O-methyl ether which reduces potency, but the 3-OH derivative is around 2200 times more potent than morphine, almost the same potency as etorphine as a μ agonist, [3] [4] and unexpectedly the 3-hydrogen compound is also around the same potency of 2000 times morphine. [5]
Unlike etorphine, 7-PET is not controlled under the UN drug conventions, but it might still be considered to be a controlled substance analogue of etorphine on the grounds of its related chemical structure in some jurisdictions such as the United States, Canada, Australia, and New Zealand.