Metodesnitazene (also known as Metazene) is a
benzimidazole derivative with
opioid effects, though unlike related compounds such as
metonitazene and
etodesnitazene which are quite potent, metodesnitazene is only around the same potency as
morphine in animal studies.[1][2][3][4][5] It is illegal in both the US and UK.
^Hunger A, Kebrle J, Rossi A, Hoffmann K (1960). "Benzimidazol-derivate und verwandte Heterocyclen. II. Synthese von 1-aminoalkyl-2-benzyl-benzimidazolen". Helvetica Chimica Acta. 43 (3): 800–809.
doi:
10.1002/hlca.19600430323.
^Vandeputte M, Van Uytfanghe K, Layle N, Germaine DS, Iula D, Stove C (12 November 2020). "Synthesis, chemical characterization, and µ-opioid receptor activity assessment of the emerging group of nitazene new synthetic opioids". Authorea.
doi:
10.22541/au.160520665.59016513/v1.
S2CID234646245.
^Ujváry I, Christie R, Evans-Brown M, Gallegos A, Jorge R, de Morais J, Sedefov R (April 2021). "DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles". ACS Chemical Neuroscience. 12 (7): 1072–1092.
doi:
10.1021/acschemneuro.1c00037.
PMID33760580.
S2CID232356192.
^Lamy FR, Daniulaityte R, Barratt MJ, Lokala U, Sheth A, Carlson RG (August 2021). ""Etazene, safer than heroin and fentanyl": Non-fentanyl novel synthetic opioid listings on one darknet market". Drug and Alcohol Dependence. 225: 108790.
doi:
10.1016/j.drugalcdep.2021.108790.
PMID34091156.
S2CID235362241.
Metodesnitazene (also known as Metazene) is a
benzimidazole derivative with
opioid effects, though unlike related compounds such as
metonitazene and
etodesnitazene which are quite potent, metodesnitazene is only around the same potency as
morphine in animal studies.[1][2][3][4][5] It is illegal in both the US and UK.
^Hunger A, Kebrle J, Rossi A, Hoffmann K (1960). "Benzimidazol-derivate und verwandte Heterocyclen. II. Synthese von 1-aminoalkyl-2-benzyl-benzimidazolen". Helvetica Chimica Acta. 43 (3): 800–809.
doi:
10.1002/hlca.19600430323.
^Vandeputte M, Van Uytfanghe K, Layle N, Germaine DS, Iula D, Stove C (12 November 2020). "Synthesis, chemical characterization, and µ-opioid receptor activity assessment of the emerging group of nitazene new synthetic opioids". Authorea.
doi:
10.22541/au.160520665.59016513/v1.
S2CID234646245.
^Ujváry I, Christie R, Evans-Brown M, Gallegos A, Jorge R, de Morais J, Sedefov R (April 2021). "DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles". ACS Chemical Neuroscience. 12 (7): 1072–1092.
doi:
10.1021/acschemneuro.1c00037.
PMID33760580.
S2CID232356192.
^Lamy FR, Daniulaityte R, Barratt MJ, Lokala U, Sheth A, Carlson RG (August 2021). ""Etazene, safer than heroin and fentanyl": Non-fentanyl novel synthetic opioid listings on one darknet market". Drug and Alcohol Dependence. 225: 108790.
doi:
10.1016/j.drugalcdep.2021.108790.
PMID34091156.
S2CID235362241.