Names | |
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IUPAC name
21-Hydroxy-5α-pregnane-3,20-dione
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Systematic IUPAC name
(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-(Hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one | |
Other names
5α-Dihydro-11-deoxycorticosterone
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Identifiers | |
3D model (
JSmol)
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ChEBI | |
ChemSpider | |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C21H32O3 | |
Molar mass | 332.484 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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5α-Dihydrodeoxycorticosterone (abbreviated as DHDOC), also known as 21-hydroxy-5α-pregnan-20-one, is an endogenous progestogen and neurosteroid. [1] It is synthesized from the adrenal hormone deoxycorticosterone (DOC) by the enzyme 5α-reductase type I. [1] DHDOC is an agonist of the progesterone receptor, as well as a positive allosteric modulator of the GABAA receptor, and is known to have anticonvulsant effects. [1] [2]
PRTooltip Progesterone receptor |
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mPRTooltip Membrane progesterone receptor ( PAQRTooltip Progestin and adipoQ receptor) |
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Alcohols | |
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Barbiturates |
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Benzodiazepines |
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Carbamates | |
Flavonoids |
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Imidazoles | |
Kava constituents | |
Monoureides | |
Neuroactive steroids |
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Nonbenzodiazepines | |
Phenols | |
Piperidinediones | |
Pyrazolopyridines | |
Quinazolinones | |
Volatiles/ gases |
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Others/unsorted |
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Names | |
---|---|
IUPAC name
21-Hydroxy-5α-pregnane-3,20-dione
| |
Systematic IUPAC name
(1S,3aS,3bR,5aS,9aS,9bS,11aS)-1-(Hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one | |
Other names
5α-Dihydro-11-deoxycorticosterone
| |
Identifiers | |
3D model (
JSmol)
|
|
ChEBI | |
ChemSpider | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C21H32O3 | |
Molar mass | 332.484 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
5α-Dihydrodeoxycorticosterone (abbreviated as DHDOC), also known as 21-hydroxy-5α-pregnan-20-one, is an endogenous progestogen and neurosteroid. [1] It is synthesized from the adrenal hormone deoxycorticosterone (DOC) by the enzyme 5α-reductase type I. [1] DHDOC is an agonist of the progesterone receptor, as well as a positive allosteric modulator of the GABAA receptor, and is known to have anticonvulsant effects. [1] [2]
Precursors | |||||||
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Corticosteroids |
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Sex steroids |
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Neurosteroids |
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Others |
PRTooltip Progesterone receptor |
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mPRTooltip Membrane progesterone receptor ( PAQRTooltip Progestin and adipoQ receptor) |
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Alcohols | |
---|---|
Barbiturates |
|
Benzodiazepines |
|
Carbamates | |
Flavonoids |
|
Imidazoles | |
Kava constituents | |
Monoureides | |
Neuroactive steroids |
|
Nonbenzodiazepines | |
Phenols | |
Piperidinediones | |
Pyrazolopyridines | |
Quinazolinones | |
Volatiles/ gases |
|
Others/unsorted |
|