Names | |
---|---|
Preferred IUPAC name
3-Methylbutanamide | |
Other names
Isopentanamide
Isovaleric acid amide Isovaleric amide beta-Methylbutyramide | |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.007.984 |
EC Number |
|
KEGG | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C5H11NO | |
Molar mass | 101.149 g·mol−1 |
Appearance | colourless solid |
Melting point | 137 °C (279 °F; 410 K) |
Boiling point | 226 °C (439 °F; 499 K) |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Isovaleramide is an organic compound with the formula (CH3)2CHCH2C(O)NH2. The amide derived from isovaleric acid, it is a colourless solid.
Isovaleramide is a constituent of valerian root.
In humans, it acts as a mild anxiolytic at lower doses and as a mild sedative at higher dosages. [1] Isovaleramide has been shown to be non- cytotoxic and does not act as a CNS stimulant. It inhibits the liver alcohol dehydrogenases and has a reported LD50 of greater than 400 mg/kg when administered intraperitoneally in mice. [2]
It is a positive allosteric modulator of the GABAA receptor, similarly to isovaleric acid. [3]
Names | |
---|---|
Preferred IUPAC name
3-Methylbutanamide | |
Other names
Isopentanamide
Isovaleric acid amide Isovaleric amide beta-Methylbutyramide | |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.007.984 |
EC Number |
|
KEGG | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C5H11NO | |
Molar mass | 101.149 g·mol−1 |
Appearance | colourless solid |
Melting point | 137 °C (279 °F; 410 K) |
Boiling point | 226 °C (439 °F; 499 K) |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Isovaleramide is an organic compound with the formula (CH3)2CHCH2C(O)NH2. The amide derived from isovaleric acid, it is a colourless solid.
Isovaleramide is a constituent of valerian root.
In humans, it acts as a mild anxiolytic at lower doses and as a mild sedative at higher dosages. [1] Isovaleramide has been shown to be non- cytotoxic and does not act as a CNS stimulant. It inhibits the liver alcohol dehydrogenases and has a reported LD50 of greater than 400 mg/kg when administered intraperitoneally in mice. [2]
It is a positive allosteric modulator of the GABAA receptor, similarly to isovaleric acid. [3]