CGS-9896 is an
anxiolytic drug used in scientific research. It has similar effects to
benzodiazepine drugs but is structurally distinct and so is classed as a
nonbenzodiazepine anxiolytic.[1]
CGS-9896 is a benzodiazepine receptor partial agonist which produces long-lasting anxiolytic and
anticonvulsant effects in animal studies but does not produce sedative effects.[2][3] It also increases appetite,[4] and reduces the development of gastrointestinal ulcers following chronic stress.[5]
References
^Leidenheimer NJ, Schechter MD (Oct 1988). "Discriminative stimulus properties of CGS 9896: interactions within the GABA/benzodiazepine receptor complex". Pharmacol Biochem Behav. 31 (2): 249–54.
doi:
10.1016/0091-3057(88)90342-5.
PMID2854261.
S2CID21773709.
^Bernasconi R, Marescaux C, Vergnes M, et al. (1988). "Evaluation of the anticonvulsant and biochemical activity of CGS 8216 and CGS 9896 in animal models". J Neural Transm. 71 (1): 11–27.
doi:
10.1007/BF01259406.
PMID3343593.
S2CID31525533.
^Rump S, Raszewski W, Gidynska T, Galecka E (1990). "Effects of CGS 9896 in acute experimental intoxication with fluostigmine". Arch. Toxicol. 64 (5): 412–3.
doi:
10.1007/BF01973465.
PMID2206111.
S2CID19084019.
^Chen SW, Davies MF, Loew GH (1995). "Food palatability and hunger modulated effects of CGS 9896 and CGS 8216 on food intake". Pharmacol Biochem Behav. 51 (2–3): 499–503.
doi:
10.1016/0091-3057(95)00020-W.
PMID7667375.
S2CID32809713.
CGS-9896 is an
anxiolytic drug used in scientific research. It has similar effects to
benzodiazepine drugs but is structurally distinct and so is classed as a
nonbenzodiazepine anxiolytic.[1]
CGS-9896 is a benzodiazepine receptor partial agonist which produces long-lasting anxiolytic and
anticonvulsant effects in animal studies but does not produce sedative effects.[2][3] It also increases appetite,[4] and reduces the development of gastrointestinal ulcers following chronic stress.[5]
References
^Leidenheimer NJ, Schechter MD (Oct 1988). "Discriminative stimulus properties of CGS 9896: interactions within the GABA/benzodiazepine receptor complex". Pharmacol Biochem Behav. 31 (2): 249–54.
doi:
10.1016/0091-3057(88)90342-5.
PMID2854261.
S2CID21773709.
^Bernasconi R, Marescaux C, Vergnes M, et al. (1988). "Evaluation of the anticonvulsant and biochemical activity of CGS 8216 and CGS 9896 in animal models". J Neural Transm. 71 (1): 11–27.
doi:
10.1007/BF01259406.
PMID3343593.
S2CID31525533.
^Rump S, Raszewski W, Gidynska T, Galecka E (1990). "Effects of CGS 9896 in acute experimental intoxication with fluostigmine". Arch. Toxicol. 64 (5): 412–3.
doi:
10.1007/BF01973465.
PMID2206111.
S2CID19084019.
^Chen SW, Davies MF, Loew GH (1995). "Food palatability and hunger modulated effects of CGS 9896 and CGS 8216 on food intake". Pharmacol Biochem Behav. 51 (2–3): 499–503.
doi:
10.1016/0091-3057(95)00020-W.
PMID7667375.
S2CID32809713.