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Names | |
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IUPAC name
(20R)-20-Hydroxypregn-4-en-3-one
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Systematic IUPAC name
(1S,3aS,3bS,9aR,9bS,11aS)-1-[(1R)-1-Hydroxyethyl]-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one | |
Other names
20β-DHP; 20β-Hydroxyprogesterone; 20β-OHP; 20β-Progesterol; 20β-Progerol; 20β-Hydroxypregn-4-en-3-one; Pregn-4-en-20β-ol-3-one
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Identifiers | |
3D model (
JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.005.137 |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C21H32O2 | |
Molar mass | 316.485 g/mol |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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20β-Dihydroprogesterone (20β-DHP), also known as 20β-hydroxyprogesterone (20β-OHP), is an endogenous metabolite of progesterone which is formed by 20β-hydroxysteroid dehydrogenase (20β-HSD). [1] It is a progestogen similarly to progesterone, with about 20 to 50% of the progestogenic activity of progesterone. [1] [2] It can be converted by 20β-HSD into progesterone in the uterus. [3] The effects of 20β-HSD on the uterus, mammary glands, and in maintaining pregnancy have been studied. [3] [4] [5] The progestogenic activity of 20β-HSD has also been characterized in women. [6] [4]
In addition to progesterone, 20α- and 20β-hydroxyprogesterone (20α- and 20β-hydroxy-4-pregnene-3-one) also are found. These compounds have about one-fifth the progestational activity of progesterone in humans and other species.
![]() | |
Names | |
---|---|
IUPAC name
(20R)-20-Hydroxypregn-4-en-3-one
| |
Systematic IUPAC name
(1S,3aS,3bS,9aR,9bS,11aS)-1-[(1R)-1-Hydroxyethyl]-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one | |
Other names
20β-DHP; 20β-Hydroxyprogesterone; 20β-OHP; 20β-Progesterol; 20β-Progerol; 20β-Hydroxypregn-4-en-3-one; Pregn-4-en-20β-ol-3-one
| |
Identifiers | |
3D model (
JSmol)
|
|
ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.005.137 |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C21H32O2 | |
Molar mass | 316.485 g/mol |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
20β-Dihydroprogesterone (20β-DHP), also known as 20β-hydroxyprogesterone (20β-OHP), is an endogenous metabolite of progesterone which is formed by 20β-hydroxysteroid dehydrogenase (20β-HSD). [1] It is a progestogen similarly to progesterone, with about 20 to 50% of the progestogenic activity of progesterone. [1] [2] It can be converted by 20β-HSD into progesterone in the uterus. [3] The effects of 20β-HSD on the uterus, mammary glands, and in maintaining pregnancy have been studied. [3] [4] [5] The progestogenic activity of 20β-HSD has also been characterized in women. [6] [4]
In addition to progesterone, 20α- and 20β-hydroxyprogesterone (20α- and 20β-hydroxy-4-pregnene-3-one) also are found. These compounds have about one-fifth the progestational activity of progesterone in humans and other species.