11-Dehydroprogesterone, also known as pregna-4,11-diene-3,20-dione, is a
steroidalprogestin that was never marketed.[1][2][3] It was found to be 2- to 3-fold as
potent as
progesterone as a
progestogen in
animalbioassays,[1][4] although other studies found them to be equivalent in potency.[2] 11-Dehydroprogesterone has been studied in women.[5] It was discovered in the 1930s or 1940s, and was one of the earliest
synthetic progestogens.[3]
^
abZarrow MX, Neher GM, Lazowasem EA, Salhanick HA (May 1957). "Biological activity of certain progesterone-like compounds as determined by the Hooker-Forbes bioassay". The Journal of Clinical Endocrinology and Metabolism. 17 (5): 658–666.
doi:
10.1210/jcem-17-5-658.
PMID13416376.
11-Dehydroprogesterone, also known as pregna-4,11-diene-3,20-dione, is a
steroidalprogestin that was never marketed.[1][2][3] It was found to be 2- to 3-fold as
potent as
progesterone as a
progestogen in
animalbioassays,[1][4] although other studies found them to be equivalent in potency.[2] 11-Dehydroprogesterone has been studied in women.[5] It was discovered in the 1930s or 1940s, and was one of the earliest
synthetic progestogens.[3]
^
abZarrow MX, Neher GM, Lazowasem EA, Salhanick HA (May 1957). "Biological activity of certain progesterone-like compounds as determined by the Hooker-Forbes bioassay". The Journal of Clinical Endocrinology and Metabolism. 17 (5): 658–666.
doi:
10.1210/jcem-17-5-658.
PMID13416376.