![]() | |
Names | |
---|---|
IUPAC name
11β,21-Dihydroxy-5α-pregnane-3,20-dione
| |
Systematic IUPAC name
(1S,3aS,3bS,5aS,9aS,9bS,10S,11aS)-10-Hydroxy-1-(hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one | |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C21H32O4 | |
Molar mass | 348.47638 g/mol |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
5α-Dihydrocorticosterone (5α-DHC, 5α-DHB), also known as 11β,21-dihydroxy-5α-pregnane-3,20-dione, is a naturally occurring, endogenous glucocorticoid steroid hormone and neurosteroid. [1] [2] [3] It is biosynthesized from corticosterone by the enzyme 5α-reductase. [4] [5] [6] DHC has central depressant effects and impairs long-term potentiation in animals. [7] [8]
![]() | |
Names | |
---|---|
IUPAC name
11β,21-Dihydroxy-5α-pregnane-3,20-dione
| |
Systematic IUPAC name
(1S,3aS,3bS,5aS,9aS,9bS,10S,11aS)-10-Hydroxy-1-(hydroxyacetyl)-9a,11a-dimethylhexadecahydro-7H-cyclopenta[a]phenanthren-7-one | |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C21H32O4 | |
Molar mass | 348.47638 g/mol |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
5α-Dihydrocorticosterone (5α-DHC, 5α-DHB), also known as 11β,21-dihydroxy-5α-pregnane-3,20-dione, is a naturally occurring, endogenous glucocorticoid steroid hormone and neurosteroid. [1] [2] [3] It is biosynthesized from corticosterone by the enzyme 5α-reductase. [4] [5] [6] DHC has central depressant effects and impairs long-term potentiation in animals. [7] [8]