From Wikipedia, the free encyclopedia
Locicortolone
Clinical data
Other namesLocicortone; RU-24476; 9α,11β-Dichloro-21-hydroxy-16α-methylpregna-1,4-diene-3,20-dione
Drug class Corticosteroid; Glucocorticoid
Identifiers
  • (8S,9R,10S,11S,13S,14S,16R,17S)-9,11-Dichloro-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard ( EPA)
Chemical and physical data
FormulaC22H28Cl2O3
Molar mass411.36 g·mol−1
3D model ( JSmol)
  • C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)CO)C)Cl)Cl)C
  • InChI=1S/C22H28Cl2O3/c1-12-8-16-15-5-4-13-9-14(26)6-7-21(13,3)22(15,24)18(23)10-20(16,2)19(12)17(27)11-25/h6-7,9,12,15-16,18-19,25H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1
  • Key:FKRMBGXNTOTQDI-IIEHVVJPSA-N

Locicortolone (developmental code name RU-24476), or locicortone, is a synthetic glucocorticoid corticosteroid which was never marketed. [1] [2]

References

  1. ^ Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 3795. ISBN  978-3-527-30247-5.
  2. ^ "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). World Health Organization. 2013. Archived from the original (PDF) on 22 October 2014.



From Wikipedia, the free encyclopedia
Locicortolone
Clinical data
Other namesLocicortone; RU-24476; 9α,11β-Dichloro-21-hydroxy-16α-methylpregna-1,4-diene-3,20-dione
Drug class Corticosteroid; Glucocorticoid
Identifiers
  • (8S,9R,10S,11S,13S,14S,16R,17S)-9,11-Dichloro-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard ( EPA)
Chemical and physical data
FormulaC22H28Cl2O3
Molar mass411.36 g·mol−1
3D model ( JSmol)
  • C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)CO)C)Cl)Cl)C
  • InChI=1S/C22H28Cl2O3/c1-12-8-16-15-5-4-13-9-14(26)6-7-21(13,3)22(15,24)18(23)10-20(16,2)19(12)17(27)11-25/h6-7,9,12,15-16,18-19,25H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1
  • Key:FKRMBGXNTOTQDI-IIEHVVJPSA-N

Locicortolone (developmental code name RU-24476), or locicortone, is a synthetic glucocorticoid corticosteroid which was never marketed. [1] [2]

References

  1. ^ Negwer M, Scharnow HG (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. p. 3795. ISBN  978-3-527-30247-5.
  2. ^ "The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances" (PDF). World Health Organization. 2013. Archived from the original (PDF) on 22 October 2014.




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