GFRA4

GFRA4
Identifiers
Aliases	GFRA4, GDNF family receptor alpha 4
External IDs	MGI: 1341873; HomoloGene: 10565; GeneCards: GFRA4; OMA: GFRA4 - orthologs
Gene location ( Human)
Chr.	Chromosome 20 (human)
End	3,663,399 bp
Gene location ( Mouse)
Chr.	Chromosome 2 (mouse)
End	130,885,008 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; periodontal fiber; ; right lobe of thyroid gland; ; prefrontal cortex; ; left lobe of thyroid gland; ; amygdala; ; hippocampus proper; ; Brodmann area 9; ; kidney;
	Top expressed in
	urinary bladder; ; striatum of neuraxis; ; superior frontal gyrus; ; primary visual cortex; ; hippocampus proper; ; dentate gyrus of hippocampal formation granule cell; ; olfactory bulb; ; substantia nigra; ; spermatocyte; ; thyroid gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	glial cell-derived neurotrophic factor receptor activity; signaling receptor activity;
Cellular component	extracellular region; membrane; anchored component of membrane; plasma membrane; intracellular anatomical structure; extracellular space; external side of plasma membrane; receptor complex;
Biological process	negative regulation of ossification; glial cell-derived neurotrophic factor receptor signaling pathway; MAPK cascade; axon guidance; nervous system development;
	Sources: Amigo / QuickGO
Orthologs
	64096
	14588
	ENSG00000125861
	ENSMUSG00000027316
	Q9GZZ7
	Q9JJT2
	NM_022139; NM_145762; NM_145763
	NM_001136063; NM_001271001; NM_001271002; NM_020014
	NP_071422; NP_665705
NP_001129535; NP_001257930; NP_001257931; NP_064398; NP_001394167;
	NP_001394168
	Wikidata
View/Edit Human	View/Edit Mouse

GDNF family receptor alpha-4 (GFRα4), also known as the persephin receptor, is a protein that in humans is encoded by the GFRA4 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125861 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027316 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GFRA4 GDNF family receptor alpha 4".

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000125861 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027316 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GFRA4 GDNF family receptor alpha 4".

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