Epigen also known as epithelial mitogen is a
protein that in humans is encoded by the EPGN
gene.[5][6]
Function
The protein encoded by this gene is a member of the
epidermal growth factor family. Members of this family are ligands for the
epidermal growth factor receptor and play a role in cell survival,
proliferation and
migration. This protein has been reported to have high
mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.[5]
Epigen also known as epithelial mitogen is a
protein that in humans is encoded by the EPGN
gene.[5][6]
Function
The protein encoded by this gene is a member of the
epidermal growth factor family. Members of this family are ligands for the
epidermal growth factor receptor and play a role in cell survival,
proliferation and
migration. This protein has been reported to have high
mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.[5]