From Wikipedia, the free encyclopedia
Glial cell line-derived neurotrophic factor receptor
Identifiers
SymbolGFRα
Pfam PF02351
InterPro IPR003438
Membranome 44
Available protein structures:
Pfam   structures / ECOD  
PDB RCSB PDB; PDBe; PDBj
PDBsum structure summary

The GDNF family receptor-α (GFRα) proteins are a group of co-receptors which form complexes with GDNF-family ligands (GFLs) to activate RET, the receptor of the GFLs. [1] The GFRα co-receptors include the following:

References

  1. ^ Enokido Y, de Sauvage F, Hongo JA, Ninkina N, Rosenthal A, Buchman VL, Davies AM (September 1998). "GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin". Current Biology. 8 (18): 1019–22. doi: 10.1016/s0960-9822(07)00422-8. PMID  9740802. S2CID  1669891.
From Wikipedia, the free encyclopedia
Glial cell line-derived neurotrophic factor receptor
Identifiers
SymbolGFRα
Pfam PF02351
InterPro IPR003438
Membranome 44
Available protein structures:
Pfam   structures / ECOD  
PDB RCSB PDB; PDBe; PDBj
PDBsum structure summary

The GDNF family receptor-α (GFRα) proteins are a group of co-receptors which form complexes with GDNF-family ligands (GFLs) to activate RET, the receptor of the GFLs. [1] The GFRα co-receptors include the following:

References

  1. ^ Enokido Y, de Sauvage F, Hongo JA, Ninkina N, Rosenthal A, Buchman VL, Davies AM (September 1998). "GFR alpha-4 and the tyrosine kinase Ret form a functional receptor complex for persephin". Current Biology. 8 (18): 1019–22. doi: 10.1016/s0960-9822(07)00422-8. PMID  9740802. S2CID  1669891.

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