Frizzled-10 (Fz-10) is a protein that in humans is encoded by the FZD10 gene. [5] [6] Fz-10 has also been designated as CD350 ( cluster of differentiation 350).
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [6]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
FZD10 | |||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | FZD10, CD350, FZ-10, Fz10, FzE7, hFz10, frizzled class receptor 10 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 606147; MGI: 2136761; HomoloGene: 21411; GeneCards: FZD10; OMA: FZD10 - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
|
Frizzled-10 (Fz-10) is a protein that in humans is encoded by the FZD10 gene. [5] [6] Fz-10 has also been designated as CD350 ( cluster of differentiation 350).
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [6]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.