From Wikipedia, the free encyclopedia
Mammalian protein found in Homo sapiens
Choline transporter-like protein 1 is a
protein that in humans is encoded by the SLC44A1
gene .
[5]
[6]
[7]
Papillary glioneuronal tumors characteristically exhibit a gene fusion between SLC44A1 and
PRKCA .
[8]
[9]
[10] Loss of function mutations have been implicated in ethanolamine transport.
[11]
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000070214 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000028412 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Wille S, Szekeres A, Majdic O, Prager E, Staffler G, Stöckl J, Kunthalert D, Prieschl EE, Baumruker T, Burtscher H, Zlabinger GJ, Knapp W, Stockinger H (November 2001).
"Characterization of CDw92 as a member of the choline transporter-like protein family regulated specifically on dendritic cells" . Journal of Immunology . 167 (10): 5795–5804.
doi :
10.4049/jimmunol.167.10.5795 .
PMID
11698453 .
^ O'Regan S, Traiffort E, Ruat M, Cha N, Compaore D, Meunier FM (February 2000).
"An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins" . Proceedings of the National Academy of Sciences of the United States of America . 97 (4): 1835–40.
Bibcode :
2000PNAS...97.1835O .
doi :
10.1073/pnas.030339697 .
PMC
26522 .
PMID
10677542 .
^
"Entrez Gene: SLC44A1 solute carrier family 44, member 1" .
^ Bridge JA, Liu XQ, Sumegi J, Nelson M, Reyes C, Bruch LA, Rosenblum M, Puccioni MJ, Bowdiono BS, McComb RD (2013).
"Identification of a Novel, Recurrent SLC44A1-PRKCA Fusion in Papillary Glioneuronal Tumor" . Brain Pathology . 23 (2): 121–128.
doi :
10.1111/j.1750-3639.2012.00612.x .
PMC
8029478 .
PMID
22725730 .
^ Pages M, Lacroix L, Tauziede-Espariat A, Castel D, Daudigeos-Dubus E, Ridola V, et al. (2015).
"Papillary glioneuronal tumors: histological and molecular characteristics and diagnostic value of SLC44A1-PRKCA fusion" . Acta Neuropathologica Communications . 3 : 85.
doi :
10.1186/s40478-015-0264-5 .
PMC
4681033 .
PMID
26671581 . 85.
^ Nagaishi M, Nobusawa S, Matsumura N, Kono F, Ishiuchi S, Abe T, Ebato M, Wang Y, Hyodo A, Yokoo H, Nakazato Y (2016). "SLC44A1 – PRKCA fusion in papillary and rosette-forming glioneuronal tumors". Journal of Clinical Neuroscience . 23 : 73–75.
doi :
10.1016/j.jocn.2015.04.021 .
PMID
26260115 .
S2CID
140207877 .
^ Taylor A, Grapentine S, Ichhpuniani J, Bakovic M (2021).
"Choline transporter-like proteins 1 and 2 are newly identified plasma membrane and mitochondrial ethanolamine transporters" . J Biol Chem . 296 : 100604.
doi :
10.1016/j.jbc.2021.100604 .
PMC
8081925 .
PMID
33789160 . {{
cite journal }}
: CS1 maint: multiple names: authors list (
link )
Yuan Z, Tie A, Tarnopolsky M, Bakovic M (June 2006).
"Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1" (PDF) . Physiological Genomics . 26 (1): 76–90.
doi :
10.1152/physiolgenomics.00107.2005 .
PMID
16609143 .
S2CID
8181779 . Archived from
the original (PDF) on 2019-03-04.
Fullerton MD, Wagner L, Yuan Z, Bakovic M (April 2006).
"Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages" (PDF) . American Journal of Physiology. Cell Physiology . 290 (4): C1230–C1238.
doi :
10.1152/ajpcell.00255.2005 .
PMID
16319125 .
S2CID
5096497 . Archived from
the original (PDF) on 2019-02-22.
Li D, Wang F, Lai M, Chen Y, Zhang JF (February 2005).
"A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C" . The Journal of Neuroscience . 25 (8): 1914–23.
doi :
10.1523/JNEUROSCI.4790-04.2005 .
PMC
6726054 .
PMID
15728831 .
Traiffort E, Ruat M, O'Regan S, Meunier FM (March 2005).
"Molecular characterization of the family of choline transporter-like proteins and their splice variants" . Journal of Neurochemistry . 92 (5): 1116–25.
doi :
10.1111/j.1471-4159.2004.02962.x .
PMID
15715662 .
S2CID
30921826 .
Lecomte MJ, De Gois S, Guerci A, Ravassard P, Faucon Biguet N, Mallet J, Berrard S (February 2005). "Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia". Molecular and Cellular Neurosciences . 28 (2): 303–13.
doi :
10.1016/j.mcn.2004.09.014 .
PMID
15691711 .
S2CID
20828310 .
Flajolet M, Rakhilin S, Wang H, Starkova N, Nuangchamnong N, Nairn AC, Greengard P (December 2003).
"Protein phosphatase 2C binds selectively to and dephosphorylates metabotropic glutamate receptor 3" . Proceedings of the National Academy of Sciences of the United States of America . 100 (26): 16006–11.
Bibcode :
2003PNAS..10016006F .
doi :
10.1073/pnas.2136600100 .
PMC
307683 .
PMID
14663150 .
Takekawa M, Maeda T, Saito H (August 1998).
"Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways" . The EMBO Journal . 17 (16): 4744–52.
doi :
10.1093/emboj/17.16.4744 .
PMC
1170803 .
PMID
9707433 .
1–50 51–100 101–150 151–200 201–250 251–300 301–350
By group
SLC1–10
(1): (2): (3): (4): (5): (6): (7): (8): (9): (10):
SLC11–20
(11): (12): (13): (14): (15): (16): (17): (18): (19): (20):
SLC21–30
(21): (22): (23): (24): (25): (26): (27): (28): (29): (30):
SLC31–40
(31): (32): (33): (34): (35): (36): (37): (38): (39): (40):
SLC41–48
(41): (42): (43): (44): (45): (46): (47): (48):