GPRC5D

GPRC5D
Identifiers
Aliases	GPRC5D, G protein-coupled receptor, class C, group 5, member D, G protein-coupled receptor class C group 5 member D
External IDs	OMIM: 607437; MGI: 1935037; HomoloGene: 10250; GeneCards: GPRC5D; OMA: GPRC5D - orthologs
Gene location ( Human)
Chr.	Chromosome 12 (human)
End	12,952,170 bp
Gene location ( Mouse)
Chr.	Chromosome 6 (mouse)
End	135,095,281 bp
RNA expression pattern
	Top expressed in
	testicle; ; upper lobe of left lung; ; hair follicle; ; mucosa of transverse colon; ; rectum; ; right lung; ; minor salivary glands; ; bone marrow cells; ; mucosa of esophagus; ; islet of Langerhans;
	Top expressed in
	lip; ; blastocyst; ; embryo; ; hair follicle; ; skin of abdomen; ; embryo; ; skin of back; ; dermis; ; skin of external ear; ; sexually immature organism;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; protein kinase activator activity;
Cellular component	integral component of membrane; plasma membrane; membrane; receptor complex; intracellular membrane-bounded organelle; extracellular exosome;
Biological process	G protein-coupled receptor signaling pathway; signal transduction; activation of protein kinase activity;
	Sources: Amigo / QuickGO
Orthologs
	55507
	93746
	ENSG00000111291
	ENSMUSG00000030205
	Q9NZD1
	Q9JIL6
	NM_018654
	NM_001205396; NM_053118
	NP_061124
	NP_001192325; NP_444348
	Wikidata
View/Edit Human	View/Edit Mouse

G-protein coupled receptor family C group 5 member D is a protein that in humans is encoded by the GPRC5D gene.^[5]

Function

The protein encoded by this gene is a member of the G protein-coupled receptor family; however, the specific function of this gene has not yet been determined.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000111291 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030205 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: GPRC5D G protein-coupled receptor, family C, group 5, member D".

Bräuner-Osborne H, Jensen AA, Sheppard PO, Brodin B, Krogsgaard-Larsen P, O'Hara P (2001). "Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D". Biochim. Biophys. Acta. 1518 (3): 237–48. doi: 10.1016/s0167-4781(01)00197-x. PMID 11311935.
Takeda S, Kadowaki S, Haga T, Takaesu H, Mitaku S (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi: 10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000111291 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030205 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GPRC5D G protein-coupled receptor, family C, group 5, member D".

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Function

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