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A sodium channel opener is a type of drug which facilitates ion transmission through sodium channels.

Examples include toxins, such as aconitine, veratridine, batrachotoxin, robustoxin, palytoxin and ciguatoxins and insecticides ( DDT and pyrethroids), which activate voltage-gated sodium channels (VGSCs), and solnatide (AP301), which activates the epithelial sodium channel (ENaC). [1]

See also

References

  1. ^ Shabbir W, Tzotzos S, Bedak M, Aufy M, Willam A, Kraihammer M, Holzner A, Czikora I, Scherbaum-Hazemi P, Fischer H, Pietschmann H, Fischer B, Lucas R, Lemmens-Gruber R (2015). "Glycosylation-dependent activation of epithelial sodium channel by solnatide". Biochem. Pharmacol. 98 (4): 740–53. doi: 10.1016/j.bcp.2015.08.003. PMID  26254591.



Stub icon

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

Retrieved from " https://en.wikipedia.org/?title=Sodium_channel_opener&oldid=1154482307"
From Wikipedia, the free encyclopedia

A sodium channel opener is a type of drug which facilitates ion transmission through sodium channels.

Examples include toxins, such as aconitine, veratridine, batrachotoxin, robustoxin, palytoxin and ciguatoxins and insecticides ( DDT and pyrethroids), which activate voltage-gated sodium channels (VGSCs), and solnatide (AP301), which activates the epithelial sodium channel (ENaC). [1]

See also

References

  1. ^ Shabbir W, Tzotzos S, Bedak M, Aufy M, Willam A, Kraihammer M, Holzner A, Czikora I, Scherbaum-Hazemi P, Fischer H, Pietschmann H, Fischer B, Lucas R, Lemmens-Gruber R (2015). "Glycosylation-dependent activation of epithelial sodium channel by solnatide". Biochem. Pharmacol. 98 (4): 740–53. doi: 10.1016/j.bcp.2015.08.003. PMID  26254591.



Stub icon

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

Retrieved from " https://en.wikipedia.org/?title=Sodium_channel_opener&oldid=1154482307"

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