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| ATC code |
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| ChEMBL | |
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| Chemical and physical data | |
| Formula | C30H42N6O5S |
| Molar mass | 598.76 g·mol−1 |
| 3D model ( JSmol) | |
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Glicaramide (SQ-65993) is an orally bioavailable anti-diabetic medication. [1] It has a similar potency as glibenclamide (glyburide) in the class of medication known as sulfonylureas. Its structure is similar since it has a cyclic acyl group which replaces the latter's 2-methoxy-5-chlorobenzyl. [2] Same as glibenclamide, it is classified as a second-generation sulfonylurea. It may have more pronounced extra-pancreatic effects than glibenclamide or tolbutamide. [2]
See also
References
- ^ Höhn H, Polacek I, Schulze E (December 1973). "Potential antidiabetic agents. Pyrazolo(3,4-b)pyridines". Journal of Medicinal Chemistry. 16 (12): 1340–6. doi: 10.1021/jm00270a006. PMID 4358224.
- ^
a
b Sarges R (1981).
"Hypoglycemic Drugs". In Ellis GP, West GB (eds.). Progress in Medicinal Chemistry. Vol. 18. Elsevier Science. p. 202.
ISBN
0-444-80345-9.
{{ cite book}}: CS1 maint: date and year ( link)
 | This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it. |
|
| |
| Clinical data | |
|---|---|
| ATC code |
|
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| ChEMBL | |
| CompTox Dashboard ( EPA) | |
| Chemical and physical data | |
| Formula | C30H42N6O5S |
| Molar mass | 598.76 g·mol−1 |
| 3D model ( JSmol) | |
| |
Glicaramide (SQ-65993) is an orally bioavailable anti-diabetic medication. [1] It has a similar potency as glibenclamide (glyburide) in the class of medication known as sulfonylureas. Its structure is similar since it has a cyclic acyl group which replaces the latter's 2-methoxy-5-chlorobenzyl. [2] Same as glibenclamide, it is classified as a second-generation sulfonylurea. It may have more pronounced extra-pancreatic effects than glibenclamide or tolbutamide. [2]
See also
References
- ^ Höhn H, Polacek I, Schulze E (December 1973). "Potential antidiabetic agents. Pyrazolo(3,4-b)pyridines". Journal of Medicinal Chemistry. 16 (12): 1340–6. doi: 10.1021/jm00270a006. PMID 4358224.
- ^
a
b Sarges R (1981).
"Hypoglycemic Drugs". In Ellis GP, West GB (eds.). Progress in Medicinal Chemistry. Vol. 18. Elsevier Science. p. 202.
ISBN
0-444-80345-9.
{{ cite book}}: CS1 maint: date and year ( link)
|
| This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it. |