From Wikipedia, the free encyclopedia
Metahexamide
Names
Preferred IUPAC name
3-Amino-N -(cyclohexylcarbamoyl)-4-methylbenzene-1-sulfonamide
Identifiers
ChEMBL
ChemSpider
ECHA InfoCard
100.008.434
KEGG
UNII
InChI=1S/C14H21N3O3S/c1-10-7-8-12(9-13(10)15)21(19,20)17-14(18)16-11-5-3-2-4-6-11/h7-9,11H,2-6,15H2,1H3,(H2,16,17,18)
N Key: XXYTXQGCRQLRHA-UHFFFAOYSA-N
N InChI=1/C14H21N3O3S/c1-10-7-8-12(9-13(10)15)21(19,20)17-14(18)16-11-5-3-2-4-6-11/h7-9,11H,2-6,15H2,1H3,(H2,16,17,18)
Key: XXYTXQGCRQLRHA-UHFFFAOYAB
CC1=C(C=C(C=C1)S(=O)(=O)NC(=O)NC2CCCCC2)N
Properties
C14 H21 N3 O3 S
Molar mass
311.4 g/mol
Pharmacology
A10BB10 (
WHO )
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
Metahexamide (
INN ) is an
anti-diabetic drug from the group of
sulfonylureas . It is long-acting and belongs to the first-generation cyclohexyl-containing sulfonylureas. It was first described in 1959.
[1]
References
fast-acting short-acting long-acting ultra-long-acting
inhalable
Calcium
VDCCs Tooltip Voltage-dependent calcium channels
Potassium
VGKCs Tooltip Voltage-gated potassium channels
IRKs Tooltip Inwardly rectifying potassium channel
KCa Tooltip Calcium-activated potassium channel
K2Ps Tooltip Tandem pore domain potassium channel
Sodium
VGSCs Tooltip Voltage-gated sodium channels
ENaC Tooltip Epithelial sodium channel
ASICs Tooltip Acid-sensing ion channel
Chloride
CaCCs Tooltip Calcium-activated chloride channel
CFTR Tooltip Cystic fibrosis transmembrane conductance regulator
Unsorted
Others
TRPs Tooltip Transient receptor potential channels
LGICs Tooltip Ligand gated ion channels