The ureidopenicillins are a group of penicillins which are active against Pseudomonas aeruginosa.[ citation needed]
There are three ureidopenicillins in clinical use: [1]
They are mostly ampicillin derivatives in which the amino acid side chain has been converted to a variety of cyclic ureas. It is speculated that the added side chain mimics a longer segment of the peptidoglycan chain, more than ampicillin, and thus would bind more easily to the penicillin-binding proteins. Ureidopenicillins are not resistant to beta-lactamases.[ citation needed]
They are used parenterally, and are particularly indicated in infections caused by Gram-negative bacteria.[ citation needed]
The ureidopenicillins are a group of penicillins which are active against Pseudomonas aeruginosa.[ citation needed]
There are three ureidopenicillins in clinical use: [1]
They are mostly ampicillin derivatives in which the amino acid side chain has been converted to a variety of cyclic ureas. It is speculated that the added side chain mimics a longer segment of the peptidoglycan chain, more than ampicillin, and thus would bind more easily to the penicillin-binding proteins. Ureidopenicillins are not resistant to beta-lactamases.[ citation needed]
They are used parenterally, and are particularly indicated in infections caused by Gram-negative bacteria.[ citation needed]