Cephems are a sub-group of β-lactam antibiotics including cephalosporins and cephamycins. [1] It is one of the most common 4-membered ring heterocycle. [2] Produced by actinomycetes, cephamycins were found to display antibacterial activity against a wide range of bacteria, including those resistant to penicillin and cephalosporins. [3] The antimicrobial properties of Cephem include the attachment to certain penicillin-binding proteins that are involved in the production of cell walls of bacteria. [4]
Researchers have developed antibiotics that include cephems and they have tried to test them clinically. [5] Many of the antibiotics that are manufactured have different efficiencies based on the amount used, their strength, and their antibacterial spectra. [5] Research was conducted on drugs that contain cephem to investigate their pharmacokinetics in the exudate of the space behind the peritoneum after radical hysterectomy and pelvic lymphadenectomy. [5]
Cephems are a sub-group of β-lactam antibiotics including cephalosporins and cephamycins. [1] It is one of the most common 4-membered ring heterocycle. [2] Produced by actinomycetes, cephamycins were found to display antibacterial activity against a wide range of bacteria, including those resistant to penicillin and cephalosporins. [3] The antimicrobial properties of Cephem include the attachment to certain penicillin-binding proteins that are involved in the production of cell walls of bacteria. [4]
Researchers have developed antibiotics that include cephems and they have tried to test them clinically. [5] Many of the antibiotics that are manufactured have different efficiencies based on the amount used, their strength, and their antibacterial spectra. [5] Research was conducted on drugs that contain cephem to investigate their pharmacokinetics in the exudate of the space behind the peritoneum after radical hysterectomy and pelvic lymphadenectomy. [5]